HLA antigens in patients with variant angina in Japan

被引：4

作者：

Kishimoto, C

Lee, JD

Shimizu, H

Ueda, T

Maruya, E

Saji, H

机构：

[1] Toyama Med & Pharmaceut Univ, Fac Med, Dept Internal Med 2, Toyama, Japan

[2] Fukui Med Sch, Dept Internal Med 1, Fukui 91011, Japan

[3] Kyoto Red Cross, Ctr Blood, Kyoto, Japan

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 1999年 / 70卷 / 03期

关键词：

variant angina; HLA antigen; genetic factors;

D O I：

10.1016/S0167-5273(99)00089-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There have been few reports on examining the susceptibility of variant angina. Accordingly, the major histocompatibility complexes (HLA-A, -B, -C, -DR) of unrelated Japanese patients with variant angina were examined. There were no significant differences in the frequency of HLA-A,-B, -C, and -DR antigens between patients and controls (n=100). Although endothelial dysfunction with pathological abnormalities is suggested to be one of the etiological factors in vasospasm, immunogenetic abnormalities linked to HLA system might not play a role in the pathogenesis of variant angina. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：249 / 252

页数：4

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