Angioedema: A potential complication of dupilumab in atopic dermatitis

被引：4

作者：

Fritz, Andrea L. ^{[1
]}

Lacy, Frank A. ^{[1
]}

Morrell, Dean S. ^{[1
]}

机构：

[1] Univ N Carolina, Dept Dermatol, 410 Market St,Suite 400, Chapel Hill, NC 27516 USA

来源：

PEDIATRIC DERMATOLOGY | 2021年 / 38卷 / 01期

关键词：

angioedema; atopic dermatitis; biologic; drug reaction; dupilumab;

D O I：

10.1111/pde.14434

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Dupilumab is a relatively new and quite effective medication for recalcitrant atopic dermatitis in patients over 6 years of age. Here, we present a 12-year-old girl with progressively worsening episodic facial swelling and erythema while treated with dupilumab. This case highlights the possibility of angioedema as an adverse effect of dupilumab treatment.

引用

页码：237 / 238

页数：2

共 6 条

[1] Dupilumab side effect in a patient with atopic dermatitis: a case report study [J].

Albader, Sakhar S. ;

Alharbi, Abdulmajeed A. ;

Alenezi, Rakan F. ;

Alsaif, Fahad M. .

BIOLOGICS-TARGETS & THERAPY, 2019, 13 :79-82

[2] Angioedema An Interdisciplinary Emergency [J].

Hahn, Janina ;

Hoffmann, Thomas K. ;

Bock, Bastian ;

Nordmann-Kleiner, Melanie ;

Trainotti, Susanne ;

Greve, Jens .

DEUTSCHES ARZTEBLATT INTERNATIONAL, 2017, 114 (29-30) :489-496

[3] Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis [J].

Simpson, E. L. ;

Bieber, T. ;

Guttman-Yassky, E. ;

Beck, L. A. ;

Blauvelt, A. ;

Cork, M. J. ;

Silverberg, J. I. ;

Deleuran, M. ;

Kataoka, Y. ;

Lacour, J. -P. ;

Kingo, K. ;

Worm, M. ;

Poulin, Y. ;

Wollenberg, A. ;

Soo, Y. ;

Graham, N. M. H. ;

Pirozzi, G. ;

Akinlade, B. ;

Staudinger, H. ;

Mastey, V. ;

Eckert, L. ;

Gadkari, A. ;

Stahl, N. ;

Yancopoulos, G. D. ;

Ardeleanu, M. .

NEW ENGLAND JOURNAL OF MEDICINE, 2016, 375 (24) :2335-2348

[4] Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis A Phase 3 Randomized Clinical Trial [J].

Simpson, Eric L. ;

Paller, Amy S. ;

Siegfried, Elaine C. ;

Boguniewicz, Mark ;

Sher, Lawrence ;

Gooderham, Melinda J. ;

Beck, Lisa A. ;

Guttman-Yassky, Emma ;

Pariser, David ;

Blauvelt, Andrew ;

Weisman, Jamie ;

Lockshin, Benjamin ;

Hultsch, Thomas ;

Zhang, Qin ;

Kamal, Mohamed A. ;

Davis, John D. ;

Akinlade, Bolanle ;

Staudinger, Heribert ;

Hamilton, Jennifer D. ;

Graham, Neil M. H. ;

Pirozzi, Gianluca ;

Gadkari, Abhijit ;

Eckert, Laurent ;

Stahl, Neil ;

Yancopoulos, George D. ;

Ruddy, Marcella ;

Bansal, Ashish .

JAMA DERMATOLOGY, 2020, 156 (01) :44-56

[5] Development or Exacerbation of Head and Neck Dermatitis in Patients Treated for Atopic Dermatitis With Dupilumab [J].

Soria, Angele ;

Du-Thanh, Aurelie ;

Seneschal, Julien ;

Jachiet, Marie ;

Staumont-Salle, Delphine ;

Barbarot, Sebastien .

JAMA DERMATOLOGY, 2019, 155 (11) :1312-1315

[6] Assessment of the Development of New Regional Dermatoses in Patients Treated for Atopic Dermatitis With Dupilumab [J].

Zhu, Gefei Alex ;

Chen, Jennifer K. ;

Chiou, Albert ;

Ko, Justin ;

Honari, Golara .

JAMA DERMATOLOGY, 2019, 155 (07) :850-852

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