INFERENCE IN SEMI-PARAMETRIC DYNAMIC MODELS FOR REPEATED COUNT DATA

This paper deals with a longitudinal semi-parametric regression model in a generalised linear model setup for repeated count data collected from a large number of independent individuals. To accommodate the longitudinal correlations, we consider a dynamic model for repeated counts which has decaying auto-correlations as the time lag increases between the repeated responses. The semi-parametric regression function involved in the model contains a specified regression function in some suitable time-dependent covariates and a non-parametric function in some other time-dependent covariates. As far as the inference is concerned, because the non-parametric function is of secondary interest, we estimate this function consistently using the independence assumption-based well-known quasilikelihood approach. Next, the proposed longitudinal correlation structure and the estimate of the non-parametric function are used to develop a semi-parametric generalised quasilikelihood approach for consistent and efficient estimation of the regression effects in the parametric regression function. The finite sample performance of the proposed estimation approach is examined through an intensive simulation study based on both large and small samples. Both balanced and unbalanced cluster sizes are incorporated in the simulation study. The asymptotic performances of the estimators are given. The estimation methodology is illustrated by reanalysing the well-known health care utilisation data consisting of counts of yearly visits to a physician by 180 individuals for four years and several important primary and secondary covariates.