Left atrial appendage occlusion: a critical appraisal updated with recent evidence

被引：2

作者：

Mandrola, John M. ^{[1
]}

Foy, Andrew J. ^{[2
]}

机构：

[1] Baptist Hlth Louisville, Louisville Cardiol Grp, Louisville, KY 40207 USA

[2] Penn State Coll Med, Div Cardiol, Hershey, PA USA

来源：

CURRENT OPINION IN CARDIOLOGY | 2020年 / 35卷 / 01期

关键词：

atrial fibrillation; left atrial appendage occlusion; stroke; Watchman; ORAL ANTICOAGULATION; STROKE PREVENTION; WATCHMAN DEVICE; WARFARIN; FIBRILLATION; CLOSURE; OUTCOMES; ASPIRIN; SAFETY;

D O I：

10.1097/HCO.0000000000000698

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose of review To allow readers to fully appreciate the uncertainties with this novel yet invasive approach to stroke prevention. Recent findings Percutaneous left atrial (LA) appendage occlusion has emerged as potential nonpharmacologic means to prevent stroke and systemic embolism in patients with atrial fibrillation. Yet the evidence underpinning this new technology is not definitive. In this review, we consider the internal and external validity of the regulatory trials, pathophysiologic basis for LA appendage occlusion and clinical tradeoffs of the procedure.

引用

页码：30 / 34

页数：5

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