Poly(ethylene glycol)-mediated mineralization of metal-organic frameworks

被引:46
作者
Yu, Qun [1 ]
Tian, Yuan [1 ]
Li, Meng [1 ]
Jiang, Yuan [1 ]
Sun, Haifeng [1 ]
Zhang, Guiqiang [1 ]
Gao, Zhiliang [1 ]
Zhang, Wei [2 ]
Hao, Jingcheng [1 ]
Hu, Ming [2 ]
Cui, Jiwei [1 ,3 ]
机构
[1] Shandong Univ, Sch Chem & Chem Engn, Key Lab Colloid & Interface Chem, Minist Educ, Jinan 250100, Shandong, Peoples R China
[2] East China Normal Univ, Sch Phys & Elect Sci, Shanghai 200241, Peoples R China
[3] Shandong Univ, State Key Lab Microbial Technol, Qingdao 266237, Shandong, Peoples R China
基金
中国国家自然科学基金;
关键词
POLYMER PARTICLES; EMBEDDING ENZYMES; FACILE SYNTHESIS; STRATEGY; DELIVERY; SURFACE; ZIF-8; SIZE; CELL;
D O I
10.1039/d0cc03734f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report a one-pot approach for the scalable synthesis of zeolitic imidazolate framework-8 nanoparticles (ZIF-8 NPs) using poly(ethylene glycol) as the mineralizer, where drugs and proteins can be encapsulated in the ZIF-8 NPs for intracellular delivery. The ZIF-8 NPs exhibit high colloidal dispersity and stability (above two weeks) in cell medium.
引用
收藏
页码:11078 / 11081
页数:4
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