Pediatric obesity: Current concepts

被引:56
作者
Greydanus, Donald E. [1 ]
Agana, Marisha [1 ]
Kamboj, Manmohan K. [2 ]
Shebrain, Saad [3 ]
Soares, Neelkamal [1 ]
Eke, Ransome [4 ]
Patel, Dilip R. [1 ]
机构
[1] Western Michigan Univ, Homer Stryker MD Sch Med, Dept Pediat & Adolescent Med, Kalamazoo, MI 49008 USA
[2] Nationwide Childrens Hosp, Sect Endocrinol Metab & Diabet, Columbus, OH USA
[3] Western Michigan Univ, Homer Stryker MD Sch Med, Dept Surg, Kalamazoo, MI 49008 USA
[4] Western Michigan Univ, Homer Stryker MD Sch Med, Dept Biomed Sci, Div Epidemiol & Biostat, Kalamazoo, MI 49008 USA
来源
DM DISEASE-A-MONTH | 2018年 / 64卷 / 04期
关键词
Obesity; Overweight; Children; Adolescents; Pharmacology; Bariatric Surgery; POLYCYSTIC-OVARY-SYNDROME; LAPAROSCOPIC SLEEVE GASTRECTOMY; BODY-MASS INDEX; MONOAMINE REUPTAKE INHIBITOR; AURANTIUM BITTER ORANGE; PULMONARY ARTERIAL-HYPERTENSION; BOMBESIN RECEPTOR SUBTYPE-3; TYPE-2; DIABETES-MELLITUS; LIFE-STYLE INTERVENTION; CHILD FEEDING PRACTICES;
D O I
10.1016/j.disamonth.2017.12.001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This discussion reflects on concepts of obesity in children and adolescents in the early 21st century. It includes reflections on its history, definition, epidemiology, diagnostic perspectives, psychosocial considerations, musculoskeletal complications, endocrine complications and principles of management. In addition to emphasis on diet and exercise, research and clinical applications in the second decade of the 21st century emphasize the increasing use of pharmacotherapy and bariatric surgery for adolescent and adult populations with critical problems of overweight and obesity. We conclude with a discussion of future directions in pediatric obesity management. (C) 2018 Elsevier Inc. All rights reserved.
引用
收藏
页码:98 / 156
页数:59
相关论文
共 533 条
[1]   Obesity: 1000 years ago [J].
Abdel-Halim, RE .
LANCET, 2005, 366 (9481) :204-204
[2]   Atherosclerotic cardiovascular disease in Egyptian women: 1570 BCE-2011 CE [J].
Abdelfattah, Alia ;
Allam, Adel H. ;
Wann, Samuel ;
Thompson, Randall C. ;
Abdel-Maksoud, Goma ;
Badr, Ibrahem ;
Amer, Hany Abdel Rahman ;
el-Din, Abd el-Halim Nur ;
Finch, Caleb E. ;
Miyamoto, Michael I. ;
Sutherland, Linda ;
Sutherland, James D. ;
Thomas, Gregory S. .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2013, 167 (02) :570-574
[3]  
Abegg K, 2017, DIABETES OBES METAB
[4]  
Acarbose Laube H., 2003, MED KLIN MUNICH, V98, P52
[5]   The MC4 receptor and control of appetite [J].
Adan, R. A. H. ;
Tiesjema, B. ;
Hillebrand, J. J. G. ;
la Fleur, S. E. ;
Kas, M. J. H. ;
de Krom, M. .
BRITISH JOURNAL OF PHARMACOLOGY, 2006, 149 (07) :815-827
[6]   A Review on SIRtuins in Diabetes [J].
Aditya, R. ;
Kiran, A. Ravi ;
Varma, D. Sai ;
Vemuri, Ravichandra ;
Gundamaraju, Rohit .
CURRENT PHARMACEUTICAL DESIGN, 2017, 23 (16) :2299-2307
[7]   Models and Strategies in the Development of Antiobesity Drugs [J].
Agahi, A. ;
Murphy, K. G. .
VETERINARY PATHOLOGY, 2014, 51 (03) :695-706
[8]   Resveratrol: Anti-Obesity Mechanisms of Action [J].
Aguirre, Leixuri ;
Fernandez-Quintela, Alfredo ;
Arias, Noemi ;
Portillo, Maria P. .
MOLECULES, 2014, 19 (11) :18632-18655
[9]   Adverse drug event monitoring at the Food and Drug Administration - Your report can make a difference [J].
Ahmad, SR .
JOURNAL OF GENERAL INTERNAL MEDICINE, 2003, 18 (01) :57-60
[10]   Metformin or Oral Contraceptives for Adolescents With Polycystic Ovarian Syndrome: A Meta-analysis [J].
Al Khalifah, Reem A. ;
Florez, Ivan D. ;
Dennis, Brittany ;
Thabane, Lehana ;
Bassilious, Ereny .
PEDIATRICS, 2016, 137 (05)