Comprehensive evaluation of risk factors for neonatal hearing loss in a large Brazilian cohort

被引：8

作者：

Anastasio, Adriana R. T. ^{[1
]}

Yamamoto, Aparecida Y. ^{[2
]}

Massuda, Eduardo T. ^{[3
]}

Manfredi, Alessandra K. S. ^{[1
]}

Cavalcante, Juliana M. S. ^{[1
]}

Lopes, Bruno C. P. ^{[3
]}

Aragon, Davi C. ^{[2
]}

Boppana, Suresh ^{[4
]}

Fowler, Karen B. ^{[4
]}

Britt, William J. ^{[4
]}

Mussi-Pinhata, Marisa M. ^{[2
]}

机构：

[1] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Hlth Sci, Sao Paulo, SP, Brazil

[2] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Pediat, Sao Paulo, SP, Brazil

[3] Univ Sao Paulo, Dept Ophthalmol Otorhinolaryngol & Head & Neck Su, Ribeirao Preto Med Sch, Sao Paulo, SP, Brazil

[4] Univ Alabama Birmingham, Dept Pediat, Birmingham, AL 35294 USA

来源：

JOURNAL OF PERINATOLOGY | 2021年 / 41卷 / 02期

基金：

巴西圣保罗研究基金会;

关键词：

BRAIN-STEM RESPONSE; NEWBORN; INFANTS; CHILDREN; PROGRAM;

D O I：

10.1038/s41372-020-00807-8

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objectives To determine the incidence and risk factors of hearing loss (HL) in Brazilian neonates. Study design 11,900 neonates were screened for hearing and congenital CMV (cCMV). Low and high-risk babies who did not pass their hearing screening and infants with cCMV were scheduled for a diagnostic audiologic evaluation. Results The incidence of HL was 2 per 1000 live-born infants (95% CI: 1-3). HL was higher in high-risk neonates than in low risk babies (18.6 vs. 0.3/1000 live births, respectively). Among infants exposed to isolated risk factors, association of HL with craniofacial abnormalities/syndromes (RR = 24.47; 95% CI: 5.9-100.9) and cCMV (RR = 9.54; 95% CI: 3.3-27.7) were observed. HL was 20 to 100-fold more likely in neonates exposed to ototoxic drugs in combination with cCMV or craniofacial/congenital anomalies. Conclusions Strategies for the prevention of cCMV and exposure to ototoxic drugs may decrease the incidence of HL in this population.

引用

页码：315 / 323

页数：9

共 34 条

[1] A decade of perovskite photovoltaics
不详
[J]. NATURE ENERGY, 2019, 4 (01) : 1 - 1
[2] Barboza AC, 2013, ACR, V18, P285, DOI DOI 10.1590/S2317-64312013000400009
[3] Universal newborn hearing screenings: A three-year experience
BarskyFirkser, L
Sun, S
[J]. PEDIATRICS, 1997, 99 (06) : art. no. - e4
[4] The universal newborn hearing screening in Brazil: From identification to intervention
Bevilacqua, Maria Cecilia
Alvarenga, Katia de Freitas
Costa, Orozimbo Alves
Mortari Moret, Adriane Lima
[J]. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2010, 74 (05) : 510 - 515
[5] Risk factors associated with hearing loss in infants: An analysis of 5282 referred neonates
Bielecki, Ireneusz
Horbulewicz, Anna
Wolan, Teresa
[J]. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2011, 75 (07) : 925 - 930
[6] Auditory neuropathy spectrum disorder (ANSD) in referrals from neonatal hearing screening at a well-baby clinic
Boudewyns, A.
Declau, Frank
van den Ende, Jenneke
Hofkens, Anouk
Dirckx, Sara
van de Heyning, Paul
[J]. EUROPEAN JOURNAL OF PEDIATRICS, 2016, 175 (07) : 993 - 1000
[7] British Columbia Early Hearing Program (BCEHP), 2012, SERV BC CHILDR HOSP
[8] Year 2007 position statement: Principles and guidelines for early hearing detection and intervention programs
Busa, Jackie
Harrison, Judy
Chappell, Jodie
Yoshinaga-Itano, Christine
Grimes, Alison
Brookhouser, Patrick E.
Epstein, Stephen
Mehl, Albert
Vohr, Betty
Gravel, Judith
Roush, Jack
Widen, Judith
Benedict, Beth S.
Scoggins, Bobbie
King, Michelle
Pippins, Linda
Savage, David H.
[J]. PEDIATRICS, 2007, 120 (04) : 898 - 921
[9] Universal newborn hearing screening and transient evoked otoacoustic emission: new concepts in Brazil
Chapchap, MJ
Segre, CM
[J]. SCANDINAVIAN AUDIOLOGY, 2001, 30 : 33 - 36
[10] Identification of neonatal hearing impairment: Infants with hearing loss
Cone-Wesson, B
Vohr, BR
Sininger, YS
Widen, JE
Folsom, RC
Gorga, MP
Norton, SJ
[J]. EAR AND HEARING, 2000, 21 (05) : 488 - 507

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