Synthesis, antimicrobial and antitubercular activity of some novel [3-isonicotinoyl-5-(4-substituted)-2,3-dihydro-1,3,4-oxadiazol-2-yl] and substituted 5-(pyridin-4-yl)-1,3,4-oxadiazole-2-thiol derivatives

被引：0

作者：

Pattan, Shashikant ^{[1
]}

Musmade, Deepak ^{[2
]}

Muluk, Rekha ^{[1
]}

Pawar, Sonali ^{[1
]}

Daithankar, Aarati ^{[1
]}

Wabale, Nikita ^{[1
]}

Bhawar, Sanjay ^{[1
]}

Pattan, Jayashri ^{[3
]}

机构：

[1] Pravara Rural Coll Pharm, Dept Pharmaceut Chem, Loni 413736, India

[2] SRESs Sanjivani Coll Pharmaceut Educ & Res, Dept Pharmaceut Chem, Kopargaon 423603, India

[3] PVP Coll Arts Sci & Commerce, Dept Biotechnol, Loni 413713, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2013年 / 52卷 / 02期

关键词：

Antibacterial; antifungal; antitubercular activity; 3-isonicotinoyl-5-(4-substituted)-2,3-dihydro-1,3,4-oxadiazol-2-yl; 5-(pyridin-4-yl)-1,3,4-oxadiazole-2-thiol; 1,3,4-OXADIAZOLE DERIVATIVES; INHIBITORS;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of aryloxadiazole and mercaptooxadiazoles have been synthesized and evaluated for antibacterial, antifungal and antitubercular activities. The newly synthesized compounds have been characterized by IR, H-1 NMR and elemental analyses. All the compounds have shown promising antibacterial, antifungal and antitubercular activity when compared with standard drug Ciprofloxacin, Griseofulvin and Streptomycin respectively.

引用

页码：293 / 299

页数：7

共 15 条

[1] Amir M, 2004, INDIAN J HETEROCY CH, V14, P51
[2] [Anonymous], 1996, IND PHARM, V2, P104
[3] Barry A.L., The antimicrobial susceptibility test: principle practices, edited by, P180
[4] Barry AL., 1976, Biol. Abstr, V64, P25783
[5] Burbuliene Milda Malvina, 2004, Farmaco (Lausanne), V59, P767, DOI 10.1016/j.farmac.2004.05.007
[6] Chandrakantha B, 2009, EUR J MED CHEM, V44
[7] Furniss BS, 1996, VOGELS TXB PRACTICAL, P1260
[8] Jakubkiene Virginija, 2003, Farmaco (Lausanne), V58, P323, DOI 10.1016/S0014-827X(02)00022-8
[9] Synthesis and pharmacological evaluation of 1,3,4-oxadiazole bearing bis(heterocycle) derivatives as anti-inflammatory and analgesic agents
Jayashankar, B.
Rai, K. M. Lokanath
Baskaran, N.
Sathish, H. S.
[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 44 (10) : 3898 - 3902
[10] Synthesis, structure, and bioactivity of N′-substituted benzylidene-3,4,5-trimethoxybenzohydrazide and 3-acetyl-2-substituted phenyl-5-(3,4,5-trimethoxyphenyl)-2,3-dihydro-1,3,4-oxadiazole derivatives
Jin, Linhong
Chen, Jiang
Song, Baoan
Chen, Zhuo
Yang, Song
Li, Qianzhu
Hu, Deyu
Xu, Ruiqing
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (19) : 5036 - 5040

← 1 2 →