Anti-cancer green bionanomaterials: present status and future prospects

被引:159
作者
Barabadi, Hamed [1 ]
Ovais, Muhammad [2 ,3 ,4 ]
Shinwari, Zabta Khan [2 ,5 ]
Saravanan, Muthupandian [6 ]
机构
[1] Shahid Beheshti Univ Med Sci, Sch Pharm, Dept Pharmaceut Biotechnol, Tehran, Iran
[2] Quaid I Azam Univ, Fac Biol Sci, Dept Biotechnol, Islamabad, Pakistan
[3] Natl Ctr Nanosci & Technol China, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing, Peoples R China
[4] Natl Ctr Nanosci & Technol China, CAS Ctr Excellence Nanosci, Beijing, Peoples R China
[5] PAS, Islamabad, Pakistan
[6] Mekelle Univ, Inst Biomed Sci, Coll Hlth Sci, Dept Med Microbiol & Immunol, Mekelle, Ethiopia
关键词
Bionanomaterials; cancer theranostics; green nanoparticles; phytosynthesis; microbial synthesis; SYNTHESIZED SILVER NANOPARTICLES; IN-VITRO CYTOTOXICITY; CERIUM OXIDE NANOPARTICLES; GOLD NANOPARTICLES; LEAF EXTRACT; CELL-LINE; BIOLOGICAL SYNTHESIS; MEDIATED SYNTHESIS; FRUIT EXTRACT; STRUCTURAL-CHARACTERIZATION;
D O I
10.1080/17518253.2017.1385856
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Cancer is one of the most common health problems responsible for outnumbered deaths worldwide. Nanomedicine plays an important role in developing alternative and more effective treatment strategies for cancer theranostics. However, the toxicity, high cost and nanoparticles (NPs) production complexity are some of the major issues that obstruct the use of existing nanomedicine. Recently, the green synthesis of biogenic NPs from plants and microbial sources has become an emerging field due to their safer, eco-friendly, simple, fast, energy efficient, low-cost and less toxic nature. Interestingly, NPs play a key role in diagnosis of tumor at the initial stage by allowing cellular visualization. Furthermore, prospective applications of green NPs include magnetically responsive drug delivery, anti-cancer activity, photo-thermal therapy and bio-imaging. The present review provides perspective on the use of anti-cancer green bionanomaterials with a focus on their present status and future prospects in the theranostics of cancer.& para;& para; [GRAPHICS] .
引用
收藏
页码:285 / 314
页数:30
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