Towards a continuous flow environment for lipase-catalyzed reactions

被引:74
作者
Itabaiana, Ivaldo, Jr. [1 ]
de Mariz e Miranda, Leandro Soter [1 ]
Mendonca Alves de Souza, Rodrigo Octavio [1 ]
机构
[1] Univ Fed Rio de Janeiro, Inst Chem, Biocatalysis & Organ Synth Grp, BR-22941909 Rio De Janeiro, Brazil
关键词
Packed bed reactor; Continuous flow; Lipases; PACKED-BED REACTOR; CANDIDA-RUGOSA LIPASE; DYNAMIC KINETIC RESOLUTION; CONJUGATED LINOLEIC-ACID; RHIZOMUCOR-MIEHEI LIPASE; SOLVENT-FREE SYSTEM; RICE BRAN OIL; IMMOBILIZED LIPASE; MASS-TRANSFER; STRUCTURED LIPIDS;
D O I
10.1016/j.molcatb.2012.08.008
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Despite the technological knowledge available for thousands years about fermentation processes, interestingly only in the last two hundred years scientists have developed tools that allow chemists to use the natural power of biocatalysts in the laboratory. The present review has covered the literature from 1991 to 2012 with the most exciting examples of lipase-catalyzed reactions under continuous flow regime. Different types of reactors can be found and in most cases a greater improvement can be observed when working under such conditions compared to the traditional batch reactors. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:1 / 9
页数:9
相关论文
共 98 条
[71]   Continuous lipase-catalyzed production of esters from crude high-oleic sunflower oil [J].
Severac, Etienne ;
Galy, Olivier ;
Turon, Fabrice ;
Monsan, Pierre ;
Marty, Alain .
BIORESOURCE TECHNOLOGY, 2011, 102 (08) :4954-4961
[72]   Selection of CalB immobilization method to be used in continuous oil transesterification: Analysis of the economical impact [J].
Severac, Etienne ;
Galy, Olivier ;
Turon, Fabrice ;
Pantel, Catherine Azzaro ;
Condoret, Jean-Stephane ;
Monsan, Pierre ;
Marty, Alain .
ENZYME AND MICROBIAL TECHNOLOGY, 2011, 48 (01) :61-70
[73]   Continuous production of structured lipid containing γ-linolenic and caprylic acids by immobilized Rhizopus delemar lipase [J].
Shimada, Y ;
Suenaga, M ;
Sugihara, A ;
Nakai, S ;
Tominaga, Y .
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1999, 76 (02) :189-193
[74]   Immobilised lipase-catalysed resolution of (R,S)-1-phenylethanol in recirculated packed bed reactor [J].
Suan, CL ;
Sarmidi, MR .
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2004, 28 (2-3) :111-119
[75]   Lipase-catalyzed kinetic resolution of 2-methylene-substituted cycloalkanols in batch and continuous-flow modes [J].
Tomin, Anna ;
Hornyanszky, Gabor ;
Kupai, Katalin ;
Dorko, Zsanett ;
Urge, Laszlo ;
Darvas, Ferenc ;
Poppe, Laszlo .
PROCESS BIOCHEMISTRY, 2010, 45 (06) :859-865
[76]   Mixed lipases for efficient enzymatic synthesis of biodiesel from used palm oil and ethanol in a solvent-free system [J].
Tongboriboon, Ketsara ;
Cheirsilp, Benjamas ;
H-Kittikun, Aran .
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2010, 67 (1-2) :52-59
[77]   Production of (S)-γ-fluoroleucine ethyl ester by enzyme mediated dynamic kinetic resolution:: Comparison of batch and fed batch stirred tank processes to a packed bed column reactor [J].
Truppo, Matthew D. ;
Pollard, David J. ;
Moore, Jeffrey C. ;
Devine, Paul N. .
CHEMICAL ENGINEERING SCIENCE, 2008, 63 (01) :122-130
[78]  
Ueda M, 2000, J BIOSCI BIOENG, V90, P125, DOI 10.1263/jbb.90.125
[79]   The kinetic resolution of 2-(4-chlorophenoxy) propionic acid using Candida rugosa lipase [J].
Ujang, Z ;
Husain, WH ;
Seng, MC ;
Rashid, AHA .
PROCESS BIOCHEMISTRY, 2003, 38 (10) :1483-1488
[80]   Continuous production of structured phospholipids in a packed red reactor with lipase from Thermomyces lanuginosa [J].
Vikbjerg, AF ;
Peng, LF ;
Mu, HL ;
Xu, XB .
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2005, 82 (04) :237-242