Ampicillin trihydrate from synchrotron powder diffraction data

被引：19
|
作者：
Burley, JC
van de Streek, J
Stephens, PW
机构：
[1] Univ Cambridge, Chem Lab, Cambridge CB2 1EW, England
[2] Cambridge Crystallog Data Ctr, Cambridge CB2 1EZ, England
[3] SUNY Stony Brook, Dept Phys & Astron, Stony Brook, NY 11794 USA
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2006年 / 62卷
关键词：
D O I：
10.1107/S1600536806001371
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The crystal structure of ampicillin trihydrate {systematic name: 6-[D(-)-alpha-aminophenylacetamido]penicillanic acid trihydrate}, C16H19N3O4S center dot 3H(2)O, a broad-spectrum beta-lactam antibiotic of the aminopenicillin type, has been determined from synchrotron X-ray powder diffraction data. The three water molecules form an infinite hydrogen-bonded chain through the crystal structure, with hydrogen bonds to the NH3+, COO-, C=O and NH groups of the ampicillin molecules.
引用
收藏
页码：O797 / O799
页数：3
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