Bioluminescent method to determine non-specific endotoxicosis in therapy

被引：0

作者：

Esimbekova, EN ^{[1
]}

Kratasyuk, VA ^{[1
]}

Abakumova, VV ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Biophys, Siberian Branch, Krasnoyarsk 660036, Russia

来源：

LUMINESCENCE | 1999年 / 14卷 / 04期

关键词：

bioluminescence; soluble luciferase; immobilized luciferase; bioluminescence analysis; endotoxicosis; therapy diseases;

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The possibility of using a bioluminescence method for measuring endotoxicosis during therapy has been investigated. Results of our experiments shown that a bioluminescence method can be used as a reliable criterion to monitor the course of disease for patients with bronchitis, ulcerous disease or chronic colecystitis. Assays using both soluble and immobilized reagents are possible. This method does not reveal differences in patients with sepsis, hepatocirrhosis or oncology. The methods are highly sensitive, rapid and simple and allow quatitative determination of the degree of seriousness of illness and estimation of the severity of a patient's condition. At present the test is used to find substances responsible for the toxic state. Copyright (C) 1999 John Wiley & Sons, Ltd.

引用

页码：197 / 198

页数：2