Immunosuppressive constituents from Saussurea medusa

被引：118
作者：
Duan, HQ
Takaishi, Y
Momota, H
Ohmoto, Y
Taki, T
机构：
[1] Univ Tokushima, Fac Pharmaceut Sci, Tokushima 7708505, Japan
[2] Otsuka Pharmaceut Co Ltd, Tokushima 77101, Japan
来源：
PHYTOCHEMISTRY | 2002年 / 59卷 / 01期
关键词：
Saussurea medusa; Compositae; lignan; phaeophorbide; immunosuppressive activity;
D O I：
10.1016/S0031-9422(01)00429-0
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The methanol extract of Saussurea medusa Maxim afforded two lignans: 2alpha-guaicyl-4-oxo-6alpha-catechyl-3,7-dioxabicyclo [3.3.0]octane and 1alpha-hydroxy-2alpha,4alpha-guaicyl-3,7-dioxabicyclo[3.3.0]octane; two chlorophyll derivatives: 13-epi-phaeophorbide-a and 13-epi-phaeophorbide-a methyl ester; one megastigmane derivative: 3-hydroxy-5alpha,6alpha-epoxy-7-megastigmen-9-one, along with 19 known compounds. Their structures were established on the basis of spectroscopic studies. (C) 2002 Elsevier Science Ltd. All rights reserved.
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页码：85 / 90
页数：6
相关论文
共 16 条
[1]   LIRIORESINOL-C DIMETHYL ETHER A DIAXIALLY SUBSTITUTED 3,7-DIOXABICYCLO[3,3,0]OCTANE LIGNAN FROM MACROPIPER EXCELSUM (FORST F) MIQ [J].
BRIGGS, LH ;
CAMBIE, RC ;
COUCH, RAF .
JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1968, (24) :3042-&
[2]  
Chan YY, 1999, CHEM PHARM BULL, V47, P887
[3]   Triterpenoids from Tripterygium wilfordii [J].
Duan, HQ ;
Takaishi, Y ;
Momota, H ;
Ohmoto, Y ;
Taki, T ;
Jia, YF ;
Li, D .
PHYTOCHEMISTRY, 2000, 53 (07) :805-810
[4]   LIGNANS FROM LEAVES OF CALOCEDRUS-FORMOSANA [J].
FANG, JM ;
HSU, KC ;
CHENG, YS .
PHYTOCHEMISTRY, 1989, 28 (12) :3553-3555
[5]  
FONSECA S F, 1978, Phytochemistry (Oxford), V17, P499, DOI 10.1016/S0031-9422(00)89347-4
[6]   STRUCTURE OF LOLIOLIDE - TERPENE FROM LOLIUM PERENNE [J].
HODGES, R ;
PORTE, AL .
TETRAHEDRON, 1964, 20 (06) :1463-&
[7]   INDUCTION OF CYTOKINES IN HUMAN PERIPHERAL-BLOOD MONONUCLEAR-CELLS BY MYCOPLASMAS [J].
KITA, M ;
OHMOTO, Y ;
HIRAI, Y ;
YAMAGUCHI, N ;
IMANISHI, J .
MICROBIOLOGY AND IMMUNOLOGY, 1992, 36 (05) :507-516
[8]  
KOBAYASHI M, 1991, CHEM PHARM BULL, V39, P3348, DOI 10.1248/cpb.39.3348
[9]   2 FLAVANONES FROM THE ROOT BARK OF LESPEDEZA-DAVIDII [J].
LI, JR ;
WANG, MS .
PHYTOCHEMISTRY, 1989, 28 (12) :3564-3566
[10]  
NAKATANI Y, 1981, CHEM PHARM BULL, V29, P2261
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