Monte Carlo modelling and simulation of cell exocytosis

被引：0

作者：

Gil, Amparo ^{[1
]}

Gonzalez-Velez, Virginia ^{[2
]}

Segura, Javier ^{[3
]}

机构：

[1] Univ Cantabria, Dept Matemat Aplicada & CC, Ave Castros S-N, E-39005 Santander, Spain

[2] UAM Azcapotzalco, Area Quim Aplicada, Mexico City 02200, DF, Mexico

[3] Univ Cantabria, Dept MATESCO, E-39005 Santander, Spain

来源：

SMO 08: PROCEEDINGS OF THE 8TH WSEAS INTERNATIONAL CONFERENCE ON SIMULATION, MODELLING AND OPTIMIZATION | 2008年

关键词：

Monte Carlo; Exocytosis; Calyx of Held; Chromaffin;

D O I：

暂无

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

We describe our Monte Carlo approach to the modelling of an active zone of an exocytotic cell, in order to study Ca2+ and secretion dynamics. Following a microscopic point of view and the stochastic nature of cell events, we have modelled the main Ca2+-regulation processes associated with hormone and neurotransmitter release. Two specific examples are considered for simulation: a nerve terminal and a chromaffin cell, which account for fast and slow exocytosis, respectively.

引用

页码：122 / +

页数：2

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