Monte Carlo modelling and simulation of cell exocytosis

被引：0
|
作者：
Gil, Amparo [1 ]
Gonzalez-Velez, Virginia [2 ]
Segura, Javier [3 ]
机构：
[1] Univ Cantabria, Dept Matemat Aplicada & CC, Ave Castros S-N, E-39005 Santander, Spain
[2] UAM Azcapotzalco, Area Quim Aplicada, Mexico City 02200, DF, Mexico
[3] Univ Cantabria, Dept MATESCO, E-39005 Santander, Spain
来源：
SMO 08: PROCEEDINGS OF THE 8TH WSEAS INTERNATIONAL CONFERENCE ON SIMULATION, MODELLING AND OPTIMIZATION | 2008年
关键词：
Monte Carlo; Exocytosis; Calyx of Held; Chromaffin;
D O I：
暂无
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
We describe our Monte Carlo approach to the modelling of an active zone of an exocytotic cell, in order to study Ca2+ and secretion dynamics. Following a microscopic point of view and the stochastic nature of cell events, we have modelled the main Ca2+-regulation processes associated with hormone and neurotransmitter release. Two specific examples are considered for simulation: a nerve terminal and a chromaffin cell, which account for fast and slow exocytosis, respectively.
引用
收藏
页码：122 / +
页数：2
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