An engineered plant peroxisome and its application in biotechnology

被引：21

作者：

Kessel-Vigelius, Sarah K. ^{[1
]}

Wiese, Jan ^{[1
]}

Schroers, Martin G. ^{[1
]}

Wrobel, Thomas J. ^{[1
]}

Hahn, Florian ^{[1
]}

Linka, Nicole ^{[1
]}

机构：

[1] Univ Dusseldorf, D-40225 Dusseldorf, Germany

来源：

PLANT SCIENCE | 2013年 / 210卷

关键词：

Peroxisome; Biotechnology; Genetic engineering; Metabolism; Stress tolerance; HEAT-SHOCK-PROTEIN; ADENINE-NUCLEOTIDE TRANSPORTER; BINDING CASSETTE TRANSPORTER; OXIDATIVE STRESS; INDOLE-3-BUTYRIC ACID; SULFUR-DIOXIDE; ASCORBATE PEROXIDASE; BACTERIAL CATALASE; TRANSGENIC PLANTS; TARGETING SIGNAL;

D O I：

10.1016/j.plantsci.2013.06.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Plant metabolic engineering is a promising tool for biotechnological applications. Major goals include enhancing plant fitness for an increased product yield and improving or introducing novel pathways to synthesize industrially relevant products. Plant peroxisomes are favorable targets for metabolic engineering, because they are involved in diverse functions, including primary and secondary metabolism, development, abiotic stress response, and pathogen defense. This review discusses targets for manipulating endogenous peroxisomal pathways, such as fatty acid beta-oxidation, or introducing novel pathways, such as the synthesis of biodegradable polymers. Furthermore, strategies to bypass peroxisomal pathways for improved energy efficiency and detoxification of environmental pollutants are discussed. In sum, we highlight the biotechnological potential of plant peroxisomes and indicate future perspectives to exploit peroxisomes as biofactories. (C) 2013 The Authors. Published by Elsevier Ireland Ltd. All rights reserved.

引用

页码：232 / 240

页数：9

共 120 条

[1]

Acosta Ivan F, 2010, Arabidopsis Book, V8, pe0129, DOI 10.1199/tab.0129

[2] Synthesis of a novel class of polyhydroxyalkanoates in Arabidopsis peroxisomes, and their use in monitoring short-chain-length intermediates of β-oxidation [J].