Dietary factors that promote or retard inflammation

被引：161

作者：

Basu, A ^{[1
]}

Devaraj, S ^{[1
]}

Jialal, I ^{[1
]}

机构：

[1] Univ Calif Davis, Med Ctr, Lab Atherosclerosis & Metab Res, Sacramento, CA 95817 USA

来源：

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY | 2006年 / 26卷 / 05期

关键词：

C-reactive protein; diet; inflammation; macronutrients; micronutrients; weight loss;

D O I：

10.1161/01.ATV.0000214295.86079.d1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Inflammation plays a pivotal role in all stages of atherosclerosis. Cardiovascular risk factors and metabolic syndrome are typified by low-grade inflammation. Intervention trials convincingly demonstrate that weight loss reduces biomarkers of inflammation, such as C-reactive protein (CRP) and interleukin (IL)-6. Limited studies have shown that certain dietary factors; oleic acid, alpha-linolenic acid, and antioxidants RRR-alpha-alpha tocopherol, reduce biomarkers of inflammation. Most of the studies with fish oil supplementation have shown null effects, and conflicting results have been reported with saturated and trans fatty acids, cholesterol, and soy intake. Much further research is needed to define the role of individual dietary factors on the biomarkers of inflammation and the mechanism of the anti-inflammatory effects of weight loss.

引用

页码：995 / 1001

页数：7

共 58 条

[1]

Baer DJ, 2004, AM J CLIN NUTR, V79, P969

[2] Increased α-linolenic acid intake lowers C-reactive protein, but has no effect on markers of atherosclerosis [J].

Bemelmans, WJE ;

Lefrandt, JD ;

Feskens, EJM ;

van Haelst, PL ;

Broer, J ;

Meyboom-de Jong, B ;

May, JF ;

Tervaert, JWC ;

Smit, AJ .

EUROPEAN JOURNAL OF CLINICAL NUTRITION, 2004, 58 (07) :1083-1089

[3] Total antioxidant capacity of the diet is inversely and independently related to plasma concentration of high-sensitivity C-reactive protein in adult Italian subjects [J].

Brighenti, F ;

Valtueña, S ;

Pellegrini, N ;

Ardigò, D ;

Del Rio, D ;

Salvatore, S ;

Piatti, P ;

Serafini, M ;

Zavaroni, I .

BRITISH JOURNAL OF NUTRITION, 2005, 93 (05) :619-625

[4]

Chan DC, 2002, CLIN CHEM, V48, P877

[5] Reduction of C-reactive protein levels through use of a multivitamin [J].

Church, TS ;

Earnest, CP ;

Wood, KA ;

Kampert, JB .

AMERICAN JOURNAL OF MEDICINE, 2003, 115 (09) :702-707

[6] Dietary fish oil decreases C-reactive protein, interleukin-6, and triacylglycerol to HDL-cholesterol ratio in postmenopausal women on HRT [J].

Ciubotaru, I ;

Lee, YS ;

Wander, RC .

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2003, 14 (09) :513-521

[7] Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) [J].

Cleeman, JI ;

Grundy, SM ;

Becker, D ;

Clark, LT ;

Cooper, RS ;

Denke, MA ;

Howard, WJ ;

Hunninghake, DB ;

Illingworth, DR ;

Luepker, RV ;

McBride, P ;

McKenney, JM ;

Pasternak, RC ;

Stone, NJ ;

Van Horn, L ;

Brewer, HB ;

Ernst, ND ;

Gordon, D ;

Levy, D ;

Rifkind, B ;

Rossouw, JE ;

Savage, P ;

Haffner, SM ;

Orloff, DG ;

Proschan, MA ;

Schwartz, JS ;

Sempos, CT ;

Shero, ST ;

Murray, EZ .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (19) :2486-2497

[8] Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction - Final report of the Lyon Diet Heart Study [J].

de Lorgeril, M ;

Salen, P ;

Martin, JL ;

Monjaud, I ;

Delaye, J ;

Mamelle, N .

CIRCULATION, 1999, 99 (06) :779-785

[9] Metabolic syndrome: an appraisal of the pro-inflammatory and procoagulant status [J].

Devaraj, S ;

Rosenson, RS ;

Jialal, I .

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 2004, 33 (02) :431-+

[10]

Dietrich M, 2005, NUTR REV, V63, P22, DOI 10.1111/j.1753-4887.2005.tb00107.x

← 1 2 3 4 5 6 →