Clostridium difficile in paediatric populations

被引:8
|
作者
Allen, Upton D. [1 ]
机构
[1] Canadian Paediat Soc, Infect Dis & Immunizat Comm, Ottawa, ON K1G 4J8, Canada
关键词
CDI; Colitis; Diarrhea; Immunocompromise; Megacolon; Metronidazole; NAP1; Vancomycin; PROTON PUMP INHIBITORS; MULTICENTER EVALUATION; FECAL BACTERIOTHERAPY; CONTROLLED-TRIAL; CYTOTOXIN ASSAY; UNITED-STATES; FUSIDIC ACID; RISK-FACTORS; DIARRHEA; INFECTION;
D O I
10.1093/pch/19.1.43
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
An increase in Clostridium difficile infection incidence has been observed among hospitalized children in the United States. The present statement, targeted at clinicians caring for infants and children in community and institutional settings, summarizes the relevant information relating to the role of C difficile in childhood diarrhea and provides recommendations for diagnosis, prevention and treatment. Significant differences between adult and paediatric risk factors and disease are discussed, along with emerging therapies. The relationship between age and disease severity in children with a newly emergent and more fluoroqinolone-resistant strain of C difficile (North American Pulse-field type-1 [NAP1]) remains unknown. The importance of antimicrobial stewardship as a preventive strategy is highlighted. This statement replaces a previous Canadian Paediatric Society position statement on C difficile published in 2000.
引用
收藏
页码:43 / 48
页数:6
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