Physicochemical properties, α-amylase and α-glucosidase inhibitory effects of the polysaccharide from leaves ofMorus albaL. under simulated gastro-intestinal digestion and its fermentation capabilityin vitroby human gut microbiota

被引：7

作者：

Wang, Chunli ^{[1
]}

Ma, Qiqi ^{[1
]}

Xue, Zihan ^{[1
]}

Li, Ruilin ^{[1
]}

Wang, Qirou ^{[1
]}

Li, Nannan ^{[1
]}

Zhang, Min ^{[2
,3
]}

Panichayupakaranant, Pharkphoom ^{[4
]}

Chen, Haixia ^{[1
]}

机构：

[1] Tianjin Univ, Sch Pharmaceut Sci & Technol, Tianjin Key Lab Modern Drug Delivery & High Effic, Tianjin 300072, Peoples R China

[2] Tianjin Agr Univ, Tianjin 300384, Peoples R China

[3] Tianjin Univ Sci & Technol, State Key Lab Nutr & Safety, Tianjin 300457, Peoples R China

[4] Prince Songkla Univ, Fac Pharmaceut Sci, Phytomed & Pharmaceut Biotechnol Excellence Ctr, Hat Yai 90112, Songkhla, Thailand

来源：

INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY | 2021年 / 56卷 / 05期

基金：

中国国家自然科学基金;

关键词：

Digestive enzymes' inhibitory effects; in vitrodigestion and fermentation; mulberry leaf polysaccharides; physicochemical properties; short-chain fatty acids; SMALL-INTESTINAL CONDITIONS; HUMAN FECAL MICROBIOTA; CHAIN FATTY-ACIDS; IN-VITRO; ANTIOXIDANT ACTIVITY; MULBERRY LEAVES; WHITE MULBERRY; L; SALIVARY; FRUIT;

D O I：

10.1111/ijfs.14759

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

The investigation aimed at determining the impact of sequential simulated digestion on the physicochemical properties and digestive enzymes inhibitory effects of the polysaccharides fraction (MLP-2) ofMorus albaL. leaves as well as itsin vitrofermentation behaviours. After artificial salivary, gastric and intestinal digestions, the chemical components and microstructure of MLP-2 were altered with significantly (P < 0.05) decreased molecular weight. The alpha-amylase and alpha-glucosidase inhibitory activities of MLP-2 were significantly (P < 0.05) improved throughout simulated digestion. MLP-2I, the intestinal digested fraction of MLP-2, could significantly (P < 0.05) decrease the pH value of fermented culture and increase the short-chain fatty acids (SCFA) concentrations, especially acetic, propionic and butyric acids. In conclusion, MLP-2 could be gradually degraded under simulated digestion with altered physicochemical properties and enhanced alpha-amylase and alpha-glucosidase inhibitory effects, and further utilised by human gut microbiota to decrease pH value and promote SCFA production.

引用

页码：2098 / 2108

页数：11

共 46 条

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