PsyGeNET: a knowledge platform on psychiatric disorders and their genes

被引:67
作者
Gutierrez-Sacristan, Alba [1 ]
Grosdidier, Solene [1 ]
Valverde, Olga [2 ]
Torrens, Marta [3 ]
Bravo, Alex [1 ]
Pinero, Janet [1 ]
Sanz, Ferran [1 ]
Furlong, Laura I. [1 ]
机构
[1] Univ Pompeu Fabra, Res Grp Integrat Biomed Informat, Res Programme Biomed Informat GRIB, Dept Expt & Hlth Sci DCEXS,Hosp del Mar Med Res I, Barcelona 08003, Spain
[2] UPF, DCEXS, IMIM, Neurobiol Behav Res Grp GReNeC, Barcelona 08003, Spain
[3] Univ Autonoma Barcelona, Inst Neuropsychiatry & Addict, Barcelona 08003, Spain
关键词
SUBSTANCE USE DISORDERS; GLOBAL BURDEN;
D O I
10.1093/bioinformatics/btv301
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
PsyGeNET (Psychiatric disorders and Genes association NETwork) is a knowledge platform for the exploratory analysis of psychiatric diseases and their associated genes. PsyGeNET is composed of a database and a web interface supporting data search, visualization, filtering and sharing. PsyGeNET integrates information from DisGeNET and data extracted from the literature by text mining, which has been curated by domain experts. It currently contains 2642 associations between 1271 genes and 37 psychiatric disease concepts. In its first release, PsyGeNET is focused on three psychiatric disorders: major depression, alcohol and cocaine use disorders. PsyGeNET represents a comprehensive, open access resource for the analysis of the molecular mechanisms underpinning psychiatric disorders and their comorbidities.
引用
收藏
页码:3075 / 3077
页数:3
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