[1] Cranfield Univ, Sch Engn, Bedford MK43 0BS, England
来源:
PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, DETC 2010, VOL 4
|
2010年
关键词:
CONTACT MECHANICS;
RESTENOSIS;
MODEL;
D O I:
暂无
中图分类号:
TH [机械、仪表工业];
学科分类号:
0802 ;
摘要:
One of the main causes for post angioplasty arterial restenosis is the excessive stress induced in the arterial wall during and after the medical intervention. The closed stent is introduced in the artery wrapped around the deflated balloon catheter and is expanded in the final position by inflating the balloon. Unfortunately, this process also stretches the arterial wall. Additionally, for the stent to be successful, its diameter must be slightly larger than the diameter of the inflated artery. The stent is usually a dense mesh of interconnected beams. Therefore, it is often considered that it applies a constant pressure to the artery / stent interface. However, in reality each beam individually presses against the innermost layer of the artery (intima). The current study proposes a model, which predicts the arterial wall subsurface stress field due to individual stent beams. It was found that the local shape of the contact (beam cross section) plays an important role close to the stent / intima contact. Sharper edged cross sections (e.g. square) promote higher stresses. It was observed that during restenosis a new inner layer (neointima) is formed, significantly reducing the stent efficiency. This could be related to local stress concentrations due to the choice of stent beam profile.
机构:
Xi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R ChinaXi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R China
Yang, Lin
Quan, Jianjun
论文数: 0引用数: 0
h-index: 0
机构:
Xi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R China
Hanzhong Cent Hosp, Dept Vasc Surg, Hanzhong, Peoples R ChinaXi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R China
Quan, Jianjun
Dong, Jian
论文数: 0引用数: 0
h-index: 0
机构:
Xi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R ChinaXi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R China
Dong, Jian
Ding, Ningning
论文数: 0引用数: 0
h-index: 0
机构:
Xi An Jiao Tong Univ, Dept Radiol, Affiliated Hosp 1, Xian, Peoples R ChinaXi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R China
Ding, Ningning
Han, Yang
论文数: 0引用数: 0
h-index: 0
机构:
Xi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R ChinaXi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R China
Han, Yang
Cong, Longlong
论文数: 0引用数: 0
h-index: 0
机构:
Xi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R ChinaXi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R China
Cong, Longlong
Lin, Yuhao
论文数: 0引用数: 0
h-index: 0
机构:
Xi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R ChinaXi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R China
Lin, Yuhao
Liu, Jianlin
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h-index: 0
机构:
Xi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R ChinaXi An Jiao Tong Univ, Dept Vasc Surg, Affiliated Hosp 1, Xian 710061, Peoples R China
机构:
Purdue Univ, Weldon Sch Biomed Engn, W Lafayette, IN 47907 USA
Indiana Univ Sch Med, Dept Cellular & Integrat Physiol, Indianapolis, IN 46202 USA
Indiana Univ Purdue Univ, Dept Biomed Engn, Indianapolis, IN 46202 USAPurdue Univ, Weldon Sch Biomed Engn, W Lafayette, IN 47907 USA
Chen, Henry Y.
Koo, Bon-Kwon
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h-index: 0
机构:
Seoul Natl Univ Hosp, Div Cardiol, Seoul 110744, South KoreaPurdue Univ, Weldon Sch Biomed Engn, W Lafayette, IN 47907 USA
Koo, Bon-Kwon
Bhatt, Deepak L.
论文数: 0引用数: 0
h-index: 0
机构:
Brigham & Womens Hosp, VA Boston Healthcare Syst, Boston, MA 02115 USA
Harvard Univ, Sch Med, Boston, MA USAPurdue Univ, Weldon Sch Biomed Engn, W Lafayette, IN 47907 USA
Bhatt, Deepak L.
Kassab, Ghassan S.
论文数: 0引用数: 0
h-index: 0
机构:
Purdue Univ, Weldon Sch Biomed Engn, W Lafayette, IN 47907 USA
Indiana Univ Sch Med, Dept Surg, Indianapolis, IN 46202 USA
Indiana Univ Sch Med, Dept Cellular & Integrat Physiol, Indianapolis, IN 46202 USA
Indiana Univ Purdue Univ, Dept Biomed Engn, Indianapolis, IN 46202 USAPurdue Univ, Weldon Sch Biomed Engn, W Lafayette, IN 47907 USA