THE INFLUENCE OF POST ANGIOPLASTY STENT IMPLANT PROFILE ON ARTERIAL WALL STRESS

被引:0
|
作者
Teodorescu, Mircea [1 ]
Brand, Moshe [1 ]
Rosen, Jacob [1 ]
Rahnejat, Homer [1 ]
机构
[1] Cranfield Univ, Sch Engn, Bedford MK43 0BS, England
来源
PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, DETC 2010, VOL 4 | 2010年
关键词
CONTACT MECHANICS; RESTENOSIS; MODEL;
D O I
暂无
中图分类号
TH [机械、仪表工业];
学科分类号
0802 ;
摘要
One of the main causes for post angioplasty arterial restenosis is the excessive stress induced in the arterial wall during and after the medical intervention. The closed stent is introduced in the artery wrapped around the deflated balloon catheter and is expanded in the final position by inflating the balloon. Unfortunately, this process also stretches the arterial wall. Additionally, for the stent to be successful, its diameter must be slightly larger than the diameter of the inflated artery. The stent is usually a dense mesh of interconnected beams. Therefore, it is often considered that it applies a constant pressure to the artery / stent interface. However, in reality each beam individually presses against the innermost layer of the artery (intima). The current study proposes a model, which predicts the arterial wall subsurface stress field due to individual stent beams. It was found that the local shape of the contact (beam cross section) plays an important role close to the stent / intima contact. Sharper edged cross sections (e.g. square) promote higher stresses. It was observed that during restenosis a new inner layer (neointima) is formed, significantly reducing the stent efficiency. This could be related to local stress concentrations due to the choice of stent beam profile.
引用
收藏
页码:413 / 420
页数:8
相关论文
共 50 条
  • [31] In Search for a Better Stent: Surrogate based Multi-Objective Optimization of Stent Design under Influence of Vessel Wall Deformation
    Putra, Narendra Kurnia
    Palar, Pramudita Satria
    Anzai, Hitomi
    Shimoyama, Koji
    Ohta, Makoto
    2017 39TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), 2017, : 1344 - 1347
  • [32] Suppression of post-angioplasty restenosis with an Akt1 siRNA-embedded coronary stent in a rabbit model
    Che, Hui-Lian
    Bae, In-Ho
    Lim, Kyung Seob
    Song, In Taek
    Lee, Haeshin
    Muthiah, Muthunarayanan
    Namgung, Ran
    Kim, Won Jong
    Kim, Dong-Gon
    Ahn, Youngkeun
    Jeong, Myung-Ho
    Park, In-Kyu
    BIOMATERIALS, 2012, 33 (33) : 8548 - 8556
  • [33] Optimal Balloon Size in Post-Stenting Angioplasty for Aortoiliac Occlusive Disease (AIOD) With Self -Expandable Nitinol Stent
    Tohoku, Shota
    Soga, Yoshimitsu
    Tomoi, Yusuke
    CIRCULATION, 2014, 130
  • [34] Investigation of the Influence of Smooth Muscle Contractions on the Properties of the Wall of a Small Arterial Vessel
    Shadrina, N. Kh.
    FLUID DYNAMICS, 2020, 55 (02) : 145 - 153
  • [35] Bioinjection treatment: Effects of post-injection residual stress on left ventricular wall stress
    Lee, Lik Chuan
    Wall, Samuel T.
    Genet, Martin
    Hinson, Andy
    Guccione, Julius M.
    JOURNAL OF BIOMECHANICS, 2014, 47 (12) : 3115 - 3119
  • [36] Therapeutic Effect of Akt1 siRNA Nanoparticle Eluting Coronary Stent on Suppression of Post-Angioplasty Restenosis
    Che, Hui-Lian
    Bae, In-Ho
    Lim, Kyung Seob
    Song, In Taek
    Lee, Haeshin
    Lee, Duhwan
    Kim, Won Jong
    Jeong, Myung-Ho
    Park, In-Kyu
    Ahn, Youngkeun
    JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2016, 12 (06) : 1211 - 1222
  • [37] Meta-Analysis of Drug-Eluting Balloon Angioplasty and Drug-Eluting Stent Placement for Infrainguinal Peripheral Arterial Disease
    Baerlocher, Mark Otto
    Kennedy, Sean Alexander
    Rajebi, Mohammad Reza
    Baerlocher, Felix J.
    Misra, Sanjay
    Liu, David
    Nikolic, Boris
    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2015, 26 (04) : 459 - 473
  • [38] Experimental study of laminar blood flow through an artery treated by a stent implantation: characterisation of intra-stent wall shear stress
    Benard, N
    Coisne, D
    Donal, E
    Perrault, R
    JOURNAL OF BIOMECHANICS, 2003, 36 (07) : 991 - 998
  • [39] The influence of angioplasty balloon sizing on acute post-procedural outcomes: a Finite Element Analysis
    Helou, B.
    Bel-Brunon, A.
    Dupont, C.
    Ye, W.
    Silvestro, C.
    Rochette, M.
    Lucas, A.
    Kaladji, A.
    Haigron, P.
    42ND ANNUAL INTERNATIONAL CONFERENCES OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY: ENABLING INNOVATIVE TECHNOLOGIES FOR GLOBAL HEALTHCARE EMBC'20, 2020, : 2536 - 2539
  • [40] Axial stent strut angle influences wall shear stress after stent implantation: analysis using 3D computational fluid dynamics models of stent foreshortening
    LaDisa, John F., Jr.
    Olson, Lars E.
    Hettrick, Douglas A.
    Warltier, David C.
    Kersten, Judy R.
    Pagel, Paul S.
    BIOMEDICAL ENGINEERING ONLINE, 2005, 4 (1)