Adipose tissue, inflammation and atherosclerosis

被引：5
作者：
Rohla, Miklos [1 ]
Weiss, Thomas W. [1 ]
机构：
[1] Wilhelminenhospital, Dept Med 3, Vienna, Austria
来源：
CLINICAL LIPIDOLOGY | 2014年 / 9卷 / 01期
关键词：
adipokines; adipose tissue; atherothrombosis; inflammatory cytokines; interleukins; metalloproteinases; PLASMINOGEN-ACTIVATOR INHIBITOR-1; CORONARY-HEART-DISEASE; TUMOR-NECROSIS-FACTOR; C-REACTIVE PROTEIN; CONVERTING ENZYME-INHIBITION; INSULIN-RESISTANCE; METABOLIC SYNDROME; INTERLEUKIN-1-BETA INHIBITION; MYOCARDIAL-INFARCTION; CARDIOVASCULAR DEATH;
D O I：
10.2217/CLP.13.80
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Extensive research in recent decades has revealed manifold metabolic functions of adipose tissue, beyond its purpose as a simple storage organ for fatty acids. Consequently, proinflammatory mediators have been identified that actively promote atherosclerosis. This review therefore highlights the complex interactions between selected cytokines and mediators originating from adipose tissue and atherothrombosis.
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页码：71 / 81
页数：11
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