Simplifying Proton NMR Spectra by Instant Homonuclear Broadband Decoupling

被引:153
作者
Meyer, N. Helge [1 ]
Zangger, Klaus [1 ]
机构
[1] Karl Franzens Univ Graz, Inst Chem Organ & Bioorgan Chem, A-8010 Graz, Austria
基金
奥地利科学基金会;
关键词
homonuclear decoupling; NMR spectroscopy; pure shift; structure elucidation; TOCSY; SPECTROSCOPY; ELIMINATION; RESOLUTION; SIGNALS; BIRD;
D O I
10.1002/anie.201300129
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Shift work: The new NMR technique, instant homonuclear decoupling, which is achieved by slice-selective homo-decoupling during acquisition, yields pure-shift NMR spectra (see picture) which can be recorded like regular 1D spectra. No special data processing is necessary and this approach can also be easily adapted for the direct dimension of two- and multidimensional spectra, giving improved resolution. © 2013 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
引用
收藏
页码:7143 / 7146
页数:4
相关论文
共 50 条
  • [41] Supercycled homonuclear dipolar decoupling in solid-state NMR:: Toward cleaner 1H spectrum and higher spinning rates
    Leskes, Michal
    Madhu, P. K.
    Vega, Shimon
    JOURNAL OF CHEMICAL PHYSICS, 2008, 128 (05)
  • [42] Broadband Heteronuclear Solid-State NMR Experiments by Exponentially Modulated Dipolar Recoupling without Decoupling
    Nielsen, Anders B.
    Straaso, Lasse A.
    Nieuwkoop, Andrew J.
    Rienstra, Chad M.
    Bjerring, Morten
    Nielsen, Niels Chr.
    JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2010, 1 (13): : 1952 - 1956
  • [43] "Perfecting" WATERGATE: clean proton NMR spectra from aqueous solution
    Adams, Ralph W.
    Holroyd, Chloe M.
    Aguilar, Juan A.
    Nilsson, Mathias
    Morris, Gareth A.
    CHEMICAL COMMUNICATIONS, 2013, 49 (04) : 358 - 360
  • [44] Improved proton decoupling in NMR spectroscopy of crystalline solids using the SPINAL-64 sequence
    Bräuniger, T
    Wormald, P
    Hodgkinson, P
    MONATSHEFTE FUR CHEMIE, 2002, 133 (12): : 1549 - 1554
  • [45] T2* weighted Deconvolution of NMR Spectra: Application to 2D Homonuclear MAS Solid-State NMR of Membrane Proteins
    Manu, V. S.
    Gopinath, Tata
    Wang, Songlin
    Veglia, Gianluigi
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [46] Simplifying Solid-State NMR Spectra for Biophysical Studies on Membrane Proteins: Selective Targeting of Sites and Interactions
    Huster, Daniel
    Madhu, Perunthiruthy K.
    BIOPHYSICAL JOURNAL, 2014, 106 (10) : 2083 - 2084
  • [47] Resolution enhancement by homonuclear J-decoupling: application to three-dimensional solid-state magic angle spinning NMR spectroscopy
    Shi, Lichi
    Peng, Xiaohu
    Ahmed, Mumdooh A. M.
    Edwards, Dale
    Brown, Leonid S.
    Ladizhansky, Vladimir
    JOURNAL OF BIOMOLECULAR NMR, 2008, 41 (01) : 9 - 15
  • [48] Fluorine-19 solid-state NMR magic-angle-turning experiments using multiple-pulse homonuclear decoupling
    Hughes, E
    Brouwer, EB
    Harris, RK
    JOURNAL OF MAGNETIC RESONANCE, 1999, 138 (02) : 256 - 267
  • [49] Resolution enhancement by homonuclear J-decoupling: application to three-dimensional solid-state magic angle spinning NMR spectroscopy
    Lichi Shi
    Xiaohu Peng
    Mumdooh A. M. Ahmed
    Dale Edwards
    Leonid S. Brown
    Vladimir Ladizhansky
    Journal of Biomolecular NMR, 2008, 41 : 9 - 15
  • [50] Towards measurement of homonuclear dipolar couplings in 1H solid-state NMR: recoupling with a rotor-synchronized decoupling scheme
    Mollica, Giulia
    Madhu, P. K.
    Ziarelli, Fabio
    Thevand, Andre
    Thureau, Pierre
    Viel, Stephane
    PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2012, 14 (13) : 4359 - 4364