BLOOD PRESSURE-INDEPENDENT RENOPROTECTION IN DIABETIC RATS TREATED WITH SMALL INTERFERING RNA TARGETING LIVER ANGIOTENSINOGEN

被引：0
|
作者：
Lopez, Edwyn Omar Cruz [1 ]
Ren, Liwei [1 ,3 ]
Uijl, Estrellita [1 ,2 ]
Clahsen-Van Groningen, Marian C. [4 ]
Van Veghel, Richard [1 ]
Garrelds, Ingrid M. [1 ]
Domenig, Oliver [5 ]
Poglitsch, Marko [5 ]
Zlatev, Ivan [6 ]
Rooney, Timothy [6 ]
Kasper, Anne [6 ]
Nioi, Paul [6 ]
Foster, Don [6 ]
Danser, A. H. Jan [1 ]
机构：
[1] Erasmus MC, Dept Internal Med, Div Vasc Med & Pharmacol, Rotterdam, Netherlands
[2] Erasmus MC, Dept Internal Med, Div Nephrol & Transplantat, Rotterdam, Netherlands
[3] Jinan Univ, Shenzhen Peoples Hosp, Translat Med Collaborat Innovat Ctr, Shenzhen, Peoples R China
[4] Erasmus MC, Dept Pathol, Rotterdam, Netherlands
[5] Attoquant Diagnost, Vienna, Austria
[6] Alnylam Pharmaceut, Cambridge, MA USA
来源：
JOURNAL OF HYPERTENSION | 2022年 / 40卷 / SUPPL期
关键词：
D O I：
暂无
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
引用
收藏
页码：E193 / E193
页数：1
相关论文
共 50 条
  • [21] Blood pressure-independent effects of valsartan on oxidative and glycation markers in type 2 diabetic subjects
    Hirose, Hiroshi
    Saisho, Yoshifumi
    Komiya, Naoko
    Saito, Ikuo
    Saruta, Takao
    JOURNAL OF HYPERTENSION, 2006, 24 : 391 - 391
  • [22] Small interfering RNA targeting CD81 ameliorated arthritis in rats
    Nakagawa, Shuji
    Arai, Yuji
    Mori, Hiroki
    Matsushita, Yumi
    Kubo, Toshikazu
    Nakanishi, Tohru
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 388 (03) : 467 - 472
  • [23] KIDNEY ARTERIOLAR RESPONSES TO LIVER-TARGETED SMALL INTERFERENCE RNA (SIRNA) TARGETING ANGIOTENSINOGEN IN DIABETIC RATS: COMPARISON WITH OTHER RENIN-ANGIOTENSIN SYSTEM BLOCKERS
    Cruz-Lopez, Edwyn
    Martini, Alexandre
    Foster, Don
    Zlatev, Ivan
    Kasper, Anne
    Sequeira-Lopez, Maria-Luisa
    Gomez, Ariel
    Danser, A. H. Jan
    JOURNAL OF HYPERTENSION, 2024, 42 (SUPPL 3)
  • [24] Blood pressure-independent neuroprotective effects of candesartan (C) but not ramipril (R) after stroke in rats
    Thoene-Reineke, C
    Krikov, M
    Mueller, S
    Neumann, C
    Villringer, A
    Unger, T
    HYPERTENSION, 2005, 46 (04) : 896 - 897
  • [25] Pharmacological stimulation of the AT2 receptor ameliorates experimental diabetic nephropathy in a blood pressure-independent manner
    Stroedr, K.
    Kraemer, S.
    Peters, H.
    Thoene-Reineke, C.
    Khadzhynov, D.
    Iliev, B.
    Th, Unger
    Steckelings, U. M.
    HYPERTENSION, 2008, 52 (04) : 771 - 771
  • [26] Blood pressure-independent increase in the cortical cerebral blood flow induced by manual acupuncture of the auricular region in rats
    Uchida, Sae
    Taniguchi, Hiroshi
    Ito, Yoshie
    Kagitani, Fusako
    JOURNAL OF PHYSIOLOGICAL SCIENCES, 2019, 69 (01) : 165 - 170
  • [27] Blood pressure-independent increase in the cortical cerebral blood flow induced by manual acupuncture of the auricular region in rats
    Sae Uchida
    Hiroshi Taniguchi
    Yoshie Ito
    Fusako Kagitani
    The Journal of Physiological Sciences, 2019, 69 : 165 - 170
  • [28] Pharmacological stimulation of the AT2 receptor ameliorates experimental diabetic nephropathy in a blood pressure-independent manner
    Kraemer, S.
    Peters, H.
    Thoene-Reineke, C.
    Khadzhynov, D.
    Stroeder, K.
    Iliev, B.
    Neumayer, H. -H.
    Unger, T.
    Steckelings, U. M.
    JOURNAL OF HYPERTENSION, 2008, 26 : S363 - S364
  • [29] Persistent beneficial effects of angiotensinogen small interfering RNA (siRNA) and valsartan in spontaneously hypertensive rats after drug removal
    Cruz-Lopez, Edwyn
    Ye, Dien
    Van Veghel, Richard
    Garrelds, Ingrid
    Kasper, Anne
    Wassarman, Kelly
    Tu, Ho-Chou
    Zlatev, Ivan
    Danser, Jan
    HYPERTENSION, 2024, 81
  • [30] Blood pressure-independent effects of losartan on endothelin-1 production in rats with chronic renal failure
    Dumont, Y
    Lebel, W
    Larivière, R
    JOURNAL OF HYPERTENSION, 2000, 18 : S214 - S214
12345