Phytochemical Analysis, Antioxidant and Antimicrobial Activities of Helichrysum arenarium (L.) Moench. and Antennaria dioica (L.) Gaertn. Flowers

被引:58
作者
Babota, Mihai [1 ]
Mocan, Andrei [1 ]
Vlase, Laurian [2 ]
Crisan, Ovidiu [3 ]
Ielciu, Irina [1 ]
Gheldiu, Ana-Maria [2 ]
Vodnar, Dan Cristian [4 ]
Crisan, Gianina [1 ]
Paltinean, Ramona [1 ]
机构
[1] Iuliu Hatieganu Univ Med & Pharm, Dept Pharmaceut Bot, Cluj Napoca 400337, Romania
[2] Iuliu Hatieganu Univ Med & Pharm, Dept Pharmaceut Technol & Biopharmaceut, Cluj Napoca 400010, Romania
[3] Iuliu Hatieganu Univ Med & Pharm, Dept Organ Chem, Cluj Napoca 400010, Romania
[4] Univ Agr Sci & Vet Med, Dept Food Sci, Cluj Napoca 400372, Romania
来源
MOLECULES | 2018年 / 23卷 / 02期
关键词
H; arenarium; A; dioica; polyphenolic profile; LC-MS; antibacterial activity; antifungal activity; antioxidant capacity; LYCIUM-BARBARUM L; PHENOLIC-COMPOUNDS; ANTIBACTERIAL ACTIVITY; POLYPHENOLIC COMPOUNDS; ASTERACEAE; PHYLOGENY; LEAVES; CONSTITUENTS; PROFILE; PLANTS;
D O I
10.3390/molecules23020409
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Antennaria dioica (L.) Gaertn. and Helichrysum arenarium (L.) Moench. are two species of the Asteraceae family, known in Romanian traditional medicine for their diuretic, choleretic, and anti-inflammatory properties. The aim of the present study was to evaluate the phenolic and sterolic composition of flowers from the two species and to assess their antioxidant, antibacterial and antifungal properties. LC-MS analyses were performed on methanolic, ethanolic and 70% v/v ethanolic extracts, before and after acid hydrolysis, and revealed high amounts of polyphenols. Chlorogenic acid was found as the main compound for the flowers of A. dioica (502.70 +/- 25.11 mg/100 g d.w.), while quercitrin was dominant in H. arenarium (424.28 +/- 21.21 mg/100 g d.w.) in 70% v/v ethanolic extracts before hydrolysis. Antioxidant capacity assays showed an important antioxidant potential, which can be correlated with the determined polyphenolic compounds, showing the 70% v/v ethanolic extracts of the two species as being the most effective antioxidant samples for the DPPH assay. Antibacterial and antifungal assays confirm a modest biological potential for the same extract of both species. Results obtained in the present study bring important data and offer scientific evidence on the chemical composition and on the biological activities of the flowers belonging to the two species.
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页数:15
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