Recurrent cellulitis with benzathine penicillin prophylaxis is associated with diabetes and psoriasis

被引:11
作者
Karppelin, M. [1 ]
Siljander, T. [2 ]
Huhtala, H. [3 ]
Aromaa, A. [4 ]
Vuopio, J. [2 ]
Hannula-Jouppi, K. [5 ]
Kere, J. [5 ,6 ,7 ]
Syrjanen, J. [1 ,8 ]
机构
[1] Tampere Univ Hosp, Dept Internal Med, Tampere 33521, Finland
[2] Natl Inst Hlth & Welf, Bacteriol Unit, Helsinki, Finland
[3] Univ Tampere, Sch Publ Hlth, FIN-33101 Tampere, Finland
[4] Natl Inst Hlth & Welf, Helsinki, Finland
[5] Univ Helsinki, Dept Med Genet, Helsinki, Finland
[6] Karolinska Inst, Dept Biosci & Nutr, Huddinge, Sweden
[7] Karolinska Inst, Clin Res Ctr, Huddinge, Sweden
[8] Univ Tampere, Sch Med, FIN-33101 Tampere, Finland
基金
芬兰科学院;
关键词
RISK-FACTORS; ERYSIPELAS; INFECTIONS;
D O I
10.1007/s10096-012-1751-2
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Risk factors for recurrent cellulitis were assessed in a case-control study including 398 patients receiving prophylactic treatment with benzathine penicillin and 8,005 controls derived from a national population-based health survey. In the multivariate analysis, psoriasis [odds ratio (OR) 3.69], other chronic dermatoses (OR 4.14), diabetes (OR 1.65), increasing body mass index (OR 1.17), increasing age (OR 1.06) and history of previous tonsillectomy (OR 6.82) were independently associated with recurrent cellulitis. Forty percent of the patients reported a cellulitis recurrence, despite ongoing benzathine penicillin prophylaxis. The role of previous tonsillectomy in recurrent cellulitis needs further evaluation.
引用
收藏
页码:369 / 372
页数:4
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