Current and Upcoming Therapies for Ocular Surface Chemical Injuries

被引：150

作者：

Baradaran-Rafii, Alireza ^{[1
]}

Eslani, Medi ^{[2
]}

Haq, Zeeshan ^{[2
]}

Shirzadeh, Ebrahim ^{[1
]}

Huvard, Michael J. ^{[2
]}

Djalilian, Ali R. ^{[2
]}

机构：

[1] Shahid Beheshti Univ Med Sci, Ophthalm Res Ctr, Tehran, Iran

[2] Univ Illinois, Dept Ophthalmol & Visual Sci, Chicago, IL USA

来源：

OCULAR SURFACE | 2017年 / 15卷 / 01期

关键词：

chemical burn; cornea; limbal stem cell deficiency; ocular chemical burn; ocular surface; stem cell; AMNIOTIC MEMBRANE TRANSPLANTATION; MESENCHYMAL STEM-CELLS; LIMBAL EPITHELIAL TRANSPLANTATION; PLATELET-RICH PLASMA; BOSTON TYPE-1 KERATOPROSTHESIS; ACELLULAR PORCINE CORNEA; CORD SERUM THERAPY; AUTOLOGOUS SERUM; ALKALI-BURN; EYE BURNS;

D O I：

10.1016/j.jtos.2016.09.002

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Chemical injuries frequently result in vision loss, disfigurement, and challenging ocular surface complications. Acute interventions are directed at decreasing the extent of the injury, suppressing inflammation, and promoting ocular surface re-epithelialization. Chronically, management involves controlling inflammation along with rehabilitation and reconstruction of the ocular surface. Future therapies aimed at inhibiting neovascularization and promoting ocular surface regeneration should provide more effective treatment options for the management of ocular chemical injuries.

引用

页码：48 / 64

页数：17

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