A new specific mechanism for the acid catalysis of the addition step in the Baeyer-Villiger rearrangement

被引：81

作者：

Alvarez-Idaboy, JR ^{[1
]}

Reyes, L ^{[1
]}

Cruz, J ^{[1
]}

机构：

[1] Univ Nacl Autonoma Mexico, Fac Quim, Mexico City 04510, DF, Mexico

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 09期

关键词：

D O I：

10.1021/ol060261z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new transition state of the addition step in the Baeyer-Villiger reaction was found. The role of proton acceptor is played by the carbonyl oxygen atom, and the free energy barrier is 12.7 kcal/mol lower than that previously reported. This finding changes the mechanism for the acid catalysis and could be of interest for similar reactions in which it is known that such catalysis occurs, especially in nonpolar solvents.

引用

页码：1763 / 1765

页数：3

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Revision C.02

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