Recent advances in micro/nano-particles for clinical detection of cancer biomarkers

被引：8

作者：

Li, Jianping ^{[1
]}

Fu, Cong ^{[1
]}

Yang, Catherine F. ^{[2
]}

机构：

[1] Guilin Univ Technol, Coll Chem & Bioengn, Guilin 541004, Peoples R China

[2] Rowan Univ, Dept Chem & Biochem, Glassboro, NJ 08028 USA

来源：

ANALYTICAL METHODS | 2013年 / 5卷 / 21期

基金：

中国国家自然科学基金;

关键词：

ENHANCED RAMAN-SCATTERING; ULTRASENSITIVE ELECTROCHEMICAL IMMUNOSENSOR; IMMUNOCHROMATOGRAPHIC TEST STRIP; SELF-ASSEMBLED MONOLAYERS; GOLD NANOPARTICLES; LABEL-FREE; CARCINOEMBRYONIC ANTIGEN; MAGNETIC NANOPARTICLES; AU NANOPARTICLES; ELECTROCHEMILUMINESCENCE IMMUNOSENSOR;

D O I：

10.1039/c3ay40791h

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Cancer is a major threat to public health and is still one of the leading causes of death worldwide. Cancer biomarkers are extremely important in the process of early detection of cancer, diagnosis, judgment of the curative effect and the prognosis. They also play an important role in mechanistic research into carcinogenesis. Detection methods based on cancer biomarkers for the determination of cancer can directly affect the diagnosis and treatment. Therefore, the development of highly sensitive and selective approaches for the detection of cancer biomarkers is critical. Micro- and nanoparticles play an important role in the clinical detection of cancer biomarkers. In this review, we provide an overview of the commonly used clinical detection methods for cancer biomarkers, such as enzyme-linked immunosorbent assay, chemiluminescence, electrochemiluminescence, as well as their technical characteristics. Additionally, various applications of recent advances in microparticles and nanoparticles in the clinical detection of cancer biomarkers are also reviewed.

引用

页码：5862 / 5874

页数：13

共 163 条

[1] Fluorescence Enhancement by Au Nanostructures: Nanoshells and Nanorods [J].

Bardhan, Rizia ;

Grady, Nathaniel K. ;

Cole, Joseph R. ;

Joshi, Amit ;

Halas, Naomi J. .

ACS NANO, 2009, 3 (03) :744-752

[2] A RADIOIMMUNOASSAY USING A MONOCLONAL-ANTIBODY TO MONITOR THE COURSE OF EPITHELIAL OVARIAN-CANCER [J].

BAST, RC ;

KLUG, TL ;

STJOHN, E ;

JENISON, E ;

NILOFF, JM ;

LAZARUS, H ;

BERKOWITZ, RS ;

LEAVITT, T ;

GRIFFITHS, CT ;

PARKER, L ;

ZURAWSKI, VR ;

KNAPP, RC .

NEW ENGLAND JOURNAL OF MEDICINE, 1983, 309 (15) :883-887

[3] Layer by layer self-assembly of thin films of metal hexacyanoferrate multilayers [J].

Bharathi, S ;

Nogami, M ;

Ikeda, S .

LANGMUIR, 2001, 17 (24) :7468-7471

[4] Solution Synthesis of a New Thermoelectric Zn1-xSb Nanophase and Its Structure Determination Using Automated Electron Diffraction Tomography [J].

Birkel, Christina S. ;

Mugnaioli, Enrico ;

Gorelik, Tatiana ;

Kolb, Ute ;

Panthoefer, Martin ;

Tremel, Wolfgang .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (28) :9881-9889

[5] Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity [J].

Boisselier, Elodie ;

Astruc, Didier .

CHEMICAL SOCIETY REVIEWS, 2009, 38 (06) :1759-1782

[6] Preparation and characterization of ordered nanoparticle and polymer composite multilayers on colloids [J].

Caruso, F ;

Möhwald, H .

LANGMUIR, 1999, 15 (23) :8276-8281

[7] A novel electrochemiluminescence strategy for ultrasensitive DNA assay using luminol functionalized gold nanoparticles multi-labeling and amplification of gold nanoparticles and biotin-streptavidin system [J].

Chai, Ying ;

Tian, Dayong ;

Wang, Wei ;

Cui, Hua .

CHEMICAL COMMUNICATIONS, 2010, 46 (40) :7560-7562

[8] Synthesis, Computed Stability, and Crystal Structure of a New Family of Inorganic Compounds: Carbonophosphates [J].

Chen, Hailong ;

Hautier, Geoffroy ;

Ceder, Gerbrand .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (48) :19619-19627

[9] Electrochemical immunosensor for carcinoembryonic antigen based on nanosilver-coated magnetic beads and gold-graphene nanolabels [J].

Chen, Huafeng ;

Tang, Dianping ;

Zhang, Bing ;

Liu, Bingqian ;

Cui, Yuling ;

Chen, Guonan .

TALANTA, 2012, 91 :95-102

[10] Aqueous one-pot synthesis of bright and ultrasmall CdTe/CdS near-infrared-emitting quantum dots and their application for tumor targeting in vivo [J].

Chen, Li-Na ;

Wang, Jing ;

Li, Wen-Tao ;

Han, He-You .

CHEMICAL COMMUNICATIONS, 2012, 48 (41) :4971-4973

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