Prenatal Diagnosis of Annular Pancreas: Reliability of the Double Bubble Sign with Periduodenal Hyperechogenic Band

被引:22
作者
Dankovcik, Robert [1 ,2 ]
Jirasek, Jan E. [3 ]
Kucera, Eduard [3 ]
Feyereisl, Jaroslav [3 ]
Radonak, Jozef
Dudas, Marek [2 ,4 ]
机构
[1] L Pasteur Univ Hosp, Dept Obstet & Gynecol 2, SK-04001 Kosice, Slovakia
[2] Safarik Univ, Kosice, Slovakia
[3] Mother & Child Care Inst Praha Podoli, Prague, Czech Republic
[4] Childrens Hosp Los Angeles, Dev Biol Program, Los Angeles, CA 90027 USA
关键词
Annular pancreas; 2-D ultrasound; Prenatal diagnosis; Double bubble; Hyperechogenic band; Differential diagnosis;
D O I
10.1159/000178759
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To evaluate the power of prenatal 2-D ultrasound examination in the 2nd trimester as a method of choice for accurate diagnosis of annular pancreas. Methods: Co-incidence of the double bubble sign (often accompanying gastroduodenal dilatation) together with a hyperechogenic band around the duodenum (corresponding with the tissue of annular pancreas) was used as a diagnostic criterion. Findings from postnatal surgery served for verification. Results: From 7,897 screened pregnancies, annular pancreas was proven in the cases where both signs were present, but never without the hyperechogenic band (N-1 = 3, N-2 = 3, p <= 0.05). Sensitivity and specificity were 100%. Conclusions: More multicentric studies are required to test this approach. The following diagnostic strategy is reasonable at the present time: when the double bubble sign is discovered, always suspect annular pancreas and look for the second sign: hyperechogenic bands around the duodenum. Also look for known associated anomalies, and vice versa, if any of associated anomalies are noted, also search specifically for the signs of annular pancreas. Copyright (C) 2008 S. Karger AG, Basel
引用
收藏
页码:483 / 490
页数:8
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