共 32 条
A Bioorthogonal Raman Reporter Strategy for SERS Detection of Glycans on Live Cells
被引:137
作者:

Lin, Liang
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Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China

Tian, Xiangdong
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机构:
Xiamen Univ, Coll Chem & Chem Engn, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China

Hong, Senlian
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h-index: 0
机构:
Peking Univ, Sch Life Sci, Beijing 100871, Peoples R China Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China

Dai, Peng
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机构:
Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China

You, Qiancheng
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机构:
Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China

Wang, Ruyi
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机构:
Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China

Feng, Lianshun
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机构:
Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China

Xie, Can
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机构:
Peking Univ, Sch Life Sci, Beijing 100871, Peoples R China Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China

Tian, Zhong-Qun
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h-index: 0
机构:
Xiamen Univ, Coll Chem & Chem Engn, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China

Chen, Xing
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h-index: 0
机构:
Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China
机构:
[1] Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China
[2] Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China
[3] Peking Univ, Sch Life Sci, Beijing 100871, Peoples R China
[4] Xiamen Univ, Coll Chem & Chem Engn, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China
基金:
中国国家自然科学基金;
关键词:
bioorthogonality;
cells;
glycans;
Raman spectroscopy;
surface science;
SCATTERING MICROSCOPY;
SIALIC-ACID;
CYCLOADDITION;
SPECTROSCOPY;
MOLECULES;
D O I:
10.1002/anie.201301387
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
Direct detection of glycans on live cells using surface-enhanced Raman scattering (SERS) has been shown. A bioorthogonal Raman reporter was directly installed onto the monosaccharide analogs. Once metabolically incorporated into cell surface glycans, the Raman reporter was detected using SERS (see picture). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:7266 / 7271
页数:6
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