Roles of lipoarabinomannan in the pathogenesis of tuberculosis

被引：127

作者：

Strohmeier, GR ^{[1
]}

Fenton, MJ ^{[1
]}

机构：

[1] Boston Univ, Sch Med, Ctr Pulm, Boston, MA 02218 USA

来源：

MICROBES AND INFECTION | 1999年 / 1卷 / 09期

关键词：

lipoarabinomannan; mycobacteria; tuberculosis; macrophage; cytokines;

D O I：

10.1016/S1286-4579(99)80072-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Tuberculosis is a worldwide public health threat caused by Mycobacterium tuberculosis. All mycobacteria express a unique cell envelope glycolipid, lipoarabinomannan, which can be released at sites of infection. Lipoarabinomannan is a potential virulence factor which ran bind to leukocytes and modulate immune responses. Here, we provide an overview of the interactions of mycobacteria and lipoarabinomannan with immune cells. (C) Elsevier, Paris.

引用

页码：709 / 717

页数：9

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