Lactobacillus fermentum strains from human breast milk with probiotic properties and cholesterol-lowering effects

被引：46

作者：

Asan-Ozusaglam, Meltem ^{[1
]}

Gunyakti, Ayse ^{[1
]}

机构：

[1] Aksaray Univ, Fac Sci & Letters, Dept Biotechnol & Mol Biol, TR-68100 Aksaray, Turkey

来源：

FOOD SCIENCE AND BIOTECHNOLOGY | 2019年 / 28卷 / 02期

关键词：

Acid and bile tolerance; Antibiotic susceptibility; Anti-cholesterol; Auto-aggregation; Transit tolerance; FOOD; BACTERIA; TOLERANCE; ABILITY; IMPACT; ACID;

D O I：

10.1007/s10068-018-0494-y

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

The study aimed to identify two lactic acid bacteria from human breast milk and evaluate for their probiotic potential. Lactobacillus fermentum strains showed various degree of antibiotic susceptibility profile to clinical commercial antibiotics. The MA-7 and MA-8 strains have never lost their vitality at pH 2 and 3. Lactobacillus fermentum MA-8 exhibited more resistance to 0.3 and 1% bile concentrations than MA-7 strain. Both of the L. fermentum strains can tolerate the simulated gastric and intestinal juices. The strains showed high auto-aggregation percentages varied from 95 to 98%. Both isolates also exhibited gamma hemolytic activity. The cholesterol lowering activity of MA-7 and MA-8 strains was varied from 34.84 to 91.15%. The supernatants showed higher anti-cholesterol activity compared to pellets. The results demonstrated that both L. fermentum strains maybe good probiotic candidates and may have potential as health biotherapeutic with cholesterol-lowering effects.

引用

页码：501 / 509

页数：9

共 41 条

[1] Selection criteria for lactic acid bacteria to be used as functional starter cultures in dry sausage production: An update [J].

Ammor, Mohammed Salim ;

Mayo, Baltasar .

MEAT SCIENCE, 2007, 76 (01) :138-146

[2]

[Anonymous], 2002, GUIDELINES EVALUATIO

[3] Screening of potential probiotic properties of Lactobacillus fermentum isolated from traditional dairy products [J].

Bao, Yan ;

Zhang, Yanchao ;

Zhang, Yong ;

Liu, Yong ;

Wang, Shiquan ;

Dong, Ximei ;

Wang, Yanyan ;

Zhang, Heping .

FOOD CONTROL, 2010, 21 (05) :695-701

[4] Impact of mode of delivery on the milk microbiota composition of healthy women [J].

Cabrera-Rubio, R. ;

Mira-Pascual, L. ;

Mira, A. ;

Collado, M. C. .

JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE, 2016, 7 (01) :54-60

[5] Beneficial effect of auto-aggregating Lactobacillus crispatus on experimentally induced colitis in mice [J].

Castagliuolo, I ;

Galeazzi, F ;

Ferrari, S ;

Elli, M ;

Brun, P ;

Cavaggioni, A ;

Tormen, D ;

Sturniolo, GC ;

Morelli, L ;

Palù, G .

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 2005, 43 (02) :197-204

[6]

Charteris WP, 1998, J APPL MICROBIOL, V84, P759

[7]

Clinical and Laboratory Standards Institute, 2012, M100S22 CLSI S

[8] Adhesion and aggregation properties of probiotic and pathogen strains [J].

Collado, Maria Carmen ;

Meriluoto, Jussi ;

Salminen, Seppo .

EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 2008, 226 (05) :1065-1073

[9]

Courvalin Patrice, 2006, Dig Liver Dis, V38 Suppl 2, pS261, DOI 10.1016/S1590-8658(07)60006-1

[10] Characterisation of Lactobacillus fermentum SM-7 isolated from koumiss, a potential probiotic bacterium with cholesterol-lowering effects [J].

Dao Dong Pan ;

Zeng, Xiao Qun ;

Yan, Yu Ting .

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2011, 91 (03) :512-518

← 1 2 3 4 5 →