Ligand- and solvent-free synthesis of 2-aminobenzothiazoles by copper-catalyzed tandem reaction of 2-haloanilines with isothiocyanates

被引：14

作者：

Yao, Ruiya ^{[1
]}

Liu, Haiyi ^{[1
]}

Wu, Yichao ^{[1
]}

Cai, Mingzhong ^{[1
]}

机构：

[1] Jiangxi Normal Univ, Dept Chem, Nanchang 330022, Peoples R China

来源：

APPLIED ORGANOMETALLIC CHEMISTRY | 2013年 / 27卷 / 02期

基金：

中国国家自然科学基金;

关键词：

copper catalysis; tandem reaction; 2-aminobenzothiazole; solvent-free; 2-haloaniline; S BOND FORMATION; BENZOTHIAZOLES; EFFICIENT; INHIBITORS;

D O I：

10.1002/aoc.2949

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

We report an environmentally friendly, efficient and practical method for the synthesis of 2-aminobenzothiazoles by a copper(II)-catalyzed tandem reaction of 2-haloanilines with isothiocyanates under ligand- and solvent-free conditions in air. The developed methodology conforms to the principles of 'green chemistry' and addresses the shortage of such methods for the synthesis of 2-aminobenzothiazoles. The reaction is quite general and generates a variety of 2-aminobenzothiazoles in good to excellent yields. Copyright (c) 2012 John Wiley & Sons, Ltd.

引用

页码：109 / 113

页数：5

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