CARBON-BASED SOLID ACID CATALYZED SYNTHESIS OF POLYHYDROQUINOLINE DERIVATIVES VIA HANTZSCH REACTION UNDER SOLVENT-FREE CONDITIONS

被引：25

作者：

Davoodnia, Abolghasem ^{[1
]}

Khojastehnezhad, Amir ^{[1
]}

机构：

[1] Islamic Azad Univ, Mashhad Branch, Dept Chem, Mashhad, Iran

来源：

JOURNAL OF THE CHILEAN CHEMICAL SOCIETY | 2012年 / 57卷 / 04期

关键词：

polyhydroquinoline derivatives; carbon-based solid acid; heterogeneous catalysis; solvent-free conditions; ONE-POT SYNTHESIS; SUPPORTED POLYPHOSPHORIC ACID; REUSABLE HETEROGENEOUS CATALYST; CALCIUM-ANTAGONISTS; IONIC LIQUID; 1,2,4,5-TETRASUBSTITUTED IMIDAZOLES; MICROWAVE IRRADIATION; FACILE SYNTHESIS; EFFICIENT; GEL;

D O I：

10.4067/S0717-97072012000400011

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An easy method for the synthesis of polyhydroquinoline derivatives via one-pot four-component Hantzsch condensation of dimedone, aryl aldehydes, ethyl acetoacetate and ammonium acetate in the presence of a catalytic amount of carbon-based solid acid (CBSA) in solvent-free conditions is described. The main advantages of the present approach are relatively short reaction times, high product yields, clean reaction profiles, simple experimental and work-up procedure.

引用

页码：1385 / 1387

页数：3

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