Role of TLX1 in T-cell acute lymphoblastic leukaemia pathogenesis

被引：10

作者：

Riz, Irene ^{[1
]}

Hawley, Teresa S. ^{[2
]}

Johnston, Helen ^{[3
]}

Hawley, Robert G. ^{[1
,3
]}

机构：

[1] George Washington Univ, Med Ctr, Dept Anat & Regenerat Biol, Washington, DC 20037 USA

[2] George Washington Univ, Med Ctr, Flow Cytometry Core Facil, Washington, DC 20037 USA

[3] George Washington Univ, Med Ctr, Program Mol Med, Washington, DC 20037 USA

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2009年 / 145卷 / 01期

关键词：

TLX1; oncogene; T-cell acute lymphoblastic leukaemia; early CD1(+) cortical thymocyte phenotype; TLX1 shRNA lentiviral vector; ONCOGENE; GENE;

D O I：

10.1111/j.1365-2141.2008.07556.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：140 / 143

页数：4

共 10 条

[1] Age-related phenotypic and oncogenic differences in T-cell acute lymphoblastic leukemias may reflect thymic atrophy [J].

Asnafi, V ;

Beldjord, K ;

Libura, M ;

Villarese, P ;

Millien, C ;

Ballerini, P ;

Kuhlein, E ;

Lafage-Pochitaloff, M ;

Delabesse, E ;

Bernard, O ;

Macintyre, E .

BLOOD, 2004, 104 (13) :4173-4180

[2] Transition from EML1-ABL1 to NUP214-ABL1 positivity in a patient with acute T-lymphoblastic leukemia [J].

De Keersmaecker, K. ;

Lahortiga, I. ;

Graux, C. ;

Marynen, P. ;

Maertens, J. ;

Cools, J. ;

Vandenberghe, P. .

LEUKEMIA, 2006, 20 (12) :2202-2204

[3] Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia [J].

Ferrando, AA ;

Neuberg, DS ;

Staunton, J ;

Loh, ML ;

Huard, C ;

Raimondi, SC ;

Behm, FG ;

Pui, CH ;

Downing, JR ;

Gilliland, DG ;

Lander, ES ;

Golub, TR ;

Look, AT .

CANCER CELL, 2002, 1 (01) :75-87

[4]

Hawley RG, 1997, CANCER RES, V57, P337

[5] Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia [J].

Lahortiga, Idoya ;

De Keersmaecker, Kim ;

Van Vlierberghe, Pieter ;

Graux, Carlos ;

Cauwelier, Barbara ;

Lambert, Frederic ;

Mentens, Nicole ;

Beverloo, H. Berna ;

Pieters, Rob ;

Speleman, Frank ;

Odero, Maria D. ;

Bauters, Marijke ;

Froyen, Guy ;

Marynen, Peter ;

Vandenberghe, Peter ;

Wlodarska, Iwona ;

Meijerink, Jules P. P. ;

Cools, Jan .

NATURE GENETICS, 2007, 39 (05) :593-595

[6] TLX1/HOX11-mediated disruption of primary thymocyte differentiation prior to the CD4+CD8+ double-positive stage [J].

Owens, BM ;

Hawley, TS ;

Spain, LM ;

Kerkel, KA ;

Hawley, RG .

BRITISH JOURNAL OF HAEMATOLOGY, 2006, 132 (02) :216-229

[7] G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia [J].

Riz, I ;

Hawley, RG .

ONCOGENE, 2005, 24 (36) :5561-5575

[8] A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups [J].

Sulong, Sarina ;

Moorman, Anthony V. ;

Irving, Julie A. E. ;

Strefford, Jonathan C. ;

Konn, Zoe J. ;

Case, Marian C. ;

Minto, Lynne ;

Barber, Kerry E. ;

Parker, Helen ;

Wright, Sarah L. ;

Stewart, Adam R. M. ;

Bailey, Simon ;

Bown, Nick P. ;

Hall, Andrew G. ;

Harrison, Christine J. .

BLOOD, 2009, 113 (01) :100-107

[9] Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia [J].

van Vlierberghe, Pieter ;

Pieters, Rob ;

Beverloo, H. Berna ;

Meijerink, Jules P. P. .

BRITISH JOURNAL OF HAEMATOLOGY, 2008, 143 (02) :153-168

[10] Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia [J].

Weng, AP ;

Ferrando, AA ;

Lee, W ;

Morris, JP ;

Silverman, LB ;

Sanchez-Irizarry, C ;

Blacklow, SC ;

Look, AT ;

Aster, JC .

SCIENCE, 2004, 306 (5694) :269-271

← 1 →