Embryonal Tumor With Abundant Neuropil and True Rosettes: A Systematic Literature Review and Report of 2 New Cases

被引:19
作者
Alexiou, George A. [1 ]
Stefanaki, Kalliopi [2 ]
Vartholomatos, George [3 ]
Sfakianos, George [1 ]
Prodromou, Neofytos [1 ]
Moschovi, Maria [4 ]
机构
[1] Childrens Hosp Agia Sofia, Dept Neurosurg, Athens, Greece
[2] Childrens Hosp Agia Sofia, Dept Pathol, Athens, Greece
[3] Univ Hosp Ioannina, Mol Biol Unit, Haematol Lab, Ioannina, Greece
[4] Univ Athens, Dept Pediat 1, Hematol Oncol Unit, Athens, Greece
关键词
brain tumor; embryonal tumor with abundant neuropil and true rosettes; BRAIN-TUMORS; ETANTR; DIFFERENTIATION; AMPLIFICATION; DIAGNOSIS; FEATURES;
D O I
10.1177/0883073812471434
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Embryonal tumor with abundant neuropil and true rosettes has been recently defined as a distinct central nervous system embryonal neoplasm, although it was initially regarded as a subtype of central nervous system primitive neuroectodermal tumor. To date 70 cases have been reported. We have performed a literature review and we present 2 new cases. Analysis of the reported data revealed that radiotherapy, tumor excision and high-dose adjuvant chemotherapy with sequential autologous hematopoietic stem cell rescue have a prognostic significance.
引用
收藏
页码:1709 / 1715
页数:7
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