Biomolecular corona on nanoparticles: a survey of recent literature and its implications in targeted drug delivery

被引:106
作者
Pearson, Ryan M. [1 ]
Juettner, Vanessa V. [1 ]
Hong, Seungpyo [1 ,2 ]
机构
[1] Univ Illinois, Dept Biopharmaceut Sci, 833 S Wood St,Rm 335, Chicago, IL 60612 USA
[2] Univ Illinois, Dept Bioengn, Chicago, IL USA
基金
美国国家科学基金会;
关键词
nanoparticle; biomolecular corona; targeted drug delivery; in vivo efficacy; PROTEIN CORONA; CONFORMATIONAL-CHANGES; BINDING; BIODISTRIBUTION; PLASMA; SIZE; NANOCARRIERS; ACCUMULATION; TRANSFERRIN; ADSORPTION;
D O I
10.3389/fchem.2014.00108
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Achieving controlled cellular responses of nanoparticles (NP) is critical for the successful development and translation of NP-based drug delivery systems. However, precise control over the physicochemical and biological properties of NPs could become convoluted, diminished, or completely lost as a result of the adsorption of biomolecules to their surfaces. Characterization of the formation of the "biomolecular" corona has thus received increased attention due to its impact on NP and protein structure as well as its negative effect on NP-based targeted drug delivery. This review presents a concise survey of the recent literature concerning the importance of the NP-biomolecule corona and how it can be utilized to improve the in vivo efficacy of targeted delivery systems.
引用
收藏
页数:7
相关论文
共 56 条
[1]   Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy [J].
Aggarwal, Parag ;
Hall, Jennifer B. ;
McLeland, Christopher B. ;
Dobrovolskaia, Marina A. ;
McNeil, Scott E. .
ADVANCED DRUG DELIVERY REVIEWS, 2009, 61 (06) :428-437
[2]   Recent advances in stealth coating of nanoparticle drug delivery systems [J].
Amoozgar, Zohreh ;
Yeo, Yoon .
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 2012, 4 (02) :219-233
[3]   Size and Surface Functionalization of Iron Oxide Nanoparticles Influence the Composition and Dynamic Nature of Their Protein Corona [J].
Ashby, Jonathan ;
Pan, Songqin ;
Zhong, Wenwan .
ACS APPLIED MATERIALS & INTERFACES, 2014, 6 (17) :15412-15419
[4]   Macrophage migration inhibitory factor: a neuroendocrine modulator of chronic inflammation [J].
Baugh, JA ;
Donnelly, SC .
JOURNAL OF ENDOCRINOLOGY, 2003, 179 (01) :15-23
[5]   Protein corona change the drug release profile of nanocarriers: The "overlooked" factor at the nanobio interface [J].
Behzadi, Shahed ;
Serpooshan, Vahid ;
Sakhtianchi, Ramin ;
Mueller, Beate ;
Landfester, Katharina ;
Crespy, Daniel ;
Mahmoudi, Morteza .
COLLOIDS AND SURFACES B-BIOINTERFACES, 2014, 123 :143-149
[6]   Magnetic Nanoparticles to Recover Cellular Organelles and Study the Time Resolved Nanoparticle-Cell Interactome throughout Uptake [J].
Bertoli, Filippo ;
Davies, Gemma-Louise ;
Monopoli, Marco P. ;
Moloney, Micheal ;
Gun'ko, Yurii K. ;
Salvati, Anna ;
Dawson, Kenneth A. .
SMALL, 2014, 10 (16) :3307-3315
[7]  
Cabral H, 2011, NAT NANOTECHNOL, V6, P815, DOI [10.1038/nnano.2011.166, 10.1038/NNANO.2011.166]
[8]   Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles [J].
Cedervall, Tommy ;
Lynch, Iseult ;
Lindman, Stina ;
Berggard, Tord ;
Thulin, Eva ;
Nilsson, Hanna ;
Dawson, Kenneth A. ;
Linse, Sara .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (07) :2050-2055
[9]   Strategies for advancing cancer nanomedicine [J].
Chauhan, Vikash P. ;
Jain, Rakesh K. .
NATURE MATERIALS, 2013, 12 (11) :958-962
[10]   Renal clearance of quantum dots [J].
Choi, Hak Soo ;
Liu, Wenhao ;
Misra, Preeti ;
Tanaka, Eiichi ;
Zimmer, John P. ;
Ipe, Binil Itty ;
Bawendi, Moungi G. ;
Frangioni, John V. .
NATURE BIOTECHNOLOGY, 2007, 25 (10) :1165-1170