Roles of EphA2 in Development and Disease

被引：57
作者：
Park, Jeong Eun [1 ]
Son, Alexander I. [1 ]
Zhou, Renping [1 ]
机构：
[1] Rutgers State Univ, Dept Biol Chem, Susan Lehman Cullman Lab Canc Res, Ernest Mario Sch Pharm, Piscataway, NJ 08854 USA
来源：
GENES | 2013年 / 4卷 / 03期
基金：
美国国家卫生研究院;
关键词：
EphA2; ephrin; development; cataract; kidney; bone; ear; mammary gland;
D O I：
10.3390/genes4030334
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The Eph family of receptor tyrosine kinases (RTKs) has been implicated in the regulation of many aspects of mammalian development. Recent analyses have revealed that the EphA2 receptor is a key modulator for a wide variety of cellular functions. This review focuses on the roles of EphA2 in both development and disease.
引用
收藏
页码：334 / 357
页数：24
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