Estimation of Monod model parameters by hybrid differential evolution

被引:39
作者
Chiou, JP
Wang, FS [1 ]
机构
[1] Natl Chung Cheng Univ, Dept Chem Engn, Chiayi 621, Taiwan
[2] Natl Chung Cheng Univ, Dept Elect Engn, Chiayi 621, Taiwan
关键词
D O I
10.1007/s004490100236
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
A hybrid method based on evolutionary algorithms is developed in this study. Two additional operations, an acceleration operation and a migration operation, are embedded into the original version of differential evolution. These two operations are used for the improvement of the convergence speed without decreasing the diversity among the individuals. The acceleration operation is used to speed up convergence. However, the migration operation is used to increase the diversity among the individuals. The hybrid method is applied to estimate the parameters of the Monod model of a recombinant fermentation process. The model profiles based on +/-50% variations of the initial concentrations of glucose can fit the experimental observations satisfactorily.
引用
收藏
页码:109 / 113
页数:5
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