Conditional alleles in mice: Practical considerations for tissue-specific knockouts

被引:110
作者
Kwan, KM [1 ]
机构
[1] Univ Texas, MD Anderson Canc Ctr, Dept Mol Genet, Houston, TX 77030 USA
关键词
conditional genetics; Cre-IoxP; Flp-FRT; tissue-specific knockout; mosaic;
D O I
10.1002/gene.10068
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
[No abstract available]
引用
收藏
页码:49 / 62
页数:14
相关论文
共 139 条
[71]  
200::AID-BIES3&gt
[72]  
3.0.CO
[73]  
2-V
[74]   Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice [J].
Ludwig, T ;
Fisher, P ;
Murty, V ;
Efstratiadis, A .
ONCOGENE, 2001, 20 (30) :3937-3948
[75]   Pax6 is required for the multipotent state of retinal progenitor cells [J].
Marquardt, T ;
Ashery-Padan, R ;
Andrejewski, N ;
Scardigli, R ;
Guillemot, F ;
Gruss, P .
CELL, 2001, 105 (01) :43-55
[76]   Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors [J].
Marszalek, JR ;
Liu, XR ;
Roberts, EA ;
Chui, D ;
Marth, JD ;
Williams, DS ;
Goldstein, LSB .
CELL, 2000, 102 (02) :175-187
[77]  
MATRSUDA M, 2001, GENE DEV, V15, P1206
[78]   Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene [J].
Meuwissen, R ;
Linn, SC ;
van der Valk, M ;
Mooi, WJ ;
Berns, A .
ONCOGENE, 2001, 20 (45) :6551-6558
[79]   An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination [J].
Meyers, EN ;
Lewandoski, M ;
Martin, GR .
NATURE GENETICS, 1998, 18 (02) :136-141
[80]   Essential role for TrkB receptors in hippocampus-mediated learning [J].
Minichiello, L ;
Korte, M ;
Wolfer, D ;
Kühn, R ;
Unsicker, K ;
Cestari, V ;
Rossi-Arnaud, C ;
Lipp, HP ;
Bonhoeffer, T ;
Klein, R .
NEURON, 1999, 24 (02) :401-414