A high-performance imaging probe with NIR luminescence and synergistically enhanced T1-T2 relaxivity for in vivo hepatic tumor targeting and multimodal imaging

被引：18

作者：

Liu, Jian ^{[1
,2
]}

Li, Zhengzheng ^{[3
]}

Yang, Xiangliang ^{[3
]}

Liu, Weisheng ^{[1
,2
]}

Wang, Baodui ^{[1
,2
]}

Zhu, Yanhong ^{[3
]}

Mu, Ketao ^{[4
]}

Zhu, Wenzhen ^{[4
]}

机构：

[1] Lanzhou Univ, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou Univ Gansu, Lanzhou 730000, Peoples R China

[2] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou Univ Gansu, Lanzhou 730000, Peoples R China

[3] Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Wuhan 430074, Peoples R China

[4] Huazhong Univ Sci & Technol, Tongji Hosp, Dept Radiol, Wuhan 430030, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 69期

基金：

中国国家自然科学基金;

关键词：

AU-FE3O4; NANOPARTICLES; GADOLINIUM; NANOCOMPOSITES;

D O I：

10.1039/c5cc04911c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A high-performance imaging probe with NIR luminescence and synergistically enhanced T-1-T-2 relaxivity was synthesized. This nanoprobe exhibits a relatively high tumor-targeting efficacy and enables NIR optical and T-1-/T-2-weighted MR imaging of hepatic tumor cells in vivo.

引用

页码：13369 / 13372

页数：4

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