N-tert-butoxycarbonyl-N,N′-ethylene-bridged (S)-tyrosyl-(S)-tyrosine methyl ester

被引:1
|
作者
Yamato, K [1 ]
Miyake, H [1 ]
Hirotsu, K [1 ]
Kojima, Y [1 ]
机构
[1] Osaka City Univ, Grad Sch Sci, Dept Chem, Sumiyoshi Ku, Osaka 558585, Japan
关键词
D O I
10.1107/S0108270199002449
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The title compound, a pseudopeptide, methyl (2S)-3-(4-hydroxyphenyl)-2-[(3S)-4-(tert-butoxycarbonyl)-3-(4-hydroxybenzyl)-2-oxopiperazin-1-yl]propionate, C26H32N2O7, was crystallized from an H2O/methanol solution. The two N-substituted chains on the piperazin-2-one (MKP) ring lie in the quasi-equatorial position and the third chain lies in the quasi-axial position. Each side chain on the tyrosines is located opposite the MKP ring. The MKP ring has a pseudo-chair form.
引用
收藏
页码:1023 / 1025
页数:3
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