Presenilins, processing of β-amyloid precursor protein, and Notch signaling

被引:57
|
作者
Chan, YM [1 ]
Jan, YN [1 ]
机构
[1] Univ Calif San Francisco, Howard Hughes Med Inst, Dept Physiol, Dept Biochem, San Francisco, CA 94143 USA
关键词
D O I
10.1016/S0896-6273(00)80771-0
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
[No abstract available]
引用
收藏
页码:201 / 204
页数:4
相关论文
共 50 条
  • [31] Amyloid precursor-like protein 1 influences endocytosis and proteolytic processing of the amyloid precursor protein
    Neumann, S
    Schöbel, S
    Jäger, S
    Trautwein, A
    Haass, C
    Pietrzik, CU
    Lichtenthaler, SF
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (11) : 7583 - 7594
  • [32] A novel ε-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with notch processing
    Weidemann, A
    Eggert, S
    Reinhard, FBM
    Vogel, M
    Paliga, K
    Baier, G
    Masters, CL
    Beyreuther, K
    Evin, G
    BIOCHEMISTRY, 2002, 41 (08) : 2825 - 2835
  • [33] Amyloid precursor protein, presenilins, and α-synuclein:: Molecular pathogenesis and pharmacological applications in Alzheimer's disease
    Suh, YH
    Checler, F
    PHARMACOLOGICAL REVIEWS, 2002, 54 (03) : 469 - 525
  • [34] Nicastrin is required for amyloid precursor protein (APP) but not Notch processing, while anterior pharynx-defective 1 is dispensable for processing of both APP and Notch
    Hu, Chen
    Zeng, Linlin
    Li, Ting
    Meyer, Michael A.
    Cui, Mei-Zhen
    Xu, Xuemin
    JOURNAL OF NEUROCHEMISTRY, 2016, 136 (06) : 1246 - 1258
  • [35] Interaction between amyloid precursor protein and presenilins in mammalian cells: Implications for the pathogenesis of Alzheimer disease
    Xia, WM
    Zhang, JM
    Perez, R
    Koo, EH
    Selkoe, DJ
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (15) : 8208 - 8213
  • [36] The Intersection of NGF/TrkA Signaling and Amyloid Precursor Protein Processing in Alzheimer's Disease Neuropathology
    Canu, Nadia
    Amadoro, Giuseppina
    Triaca, Viviana
    Latina, Valentina
    Sposato, Valentina
    Corsetti, Veronica
    Severini, Cinzia
    Ciotti, Maria Teresa
    Calissano, Pietro
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (06)
  • [37] Amyloid precursor protein activates phosphotyrosine signaling pathway
    MookJung, I
    Saitoh, T
    NEUROSCIENCE LETTERS, 1997, 235 (1-2) : 1 - 4
  • [38] Inhibition of Wnt signaling induces amyloidogenic processing of amyloid precursor protein and the production and aggregation of Amyloid-β (Aβ)42 peptides
    Tapia-Rojas, Cheril
    Burgos, Patricia V.
    Inestrosa, Nibaldo C.
    JOURNAL OF NEUROCHEMISTRY, 2016, 139 (06) : 1175 - 1191
  • [39] Amyloid precursor protein and presenilin involvement in cell signaling
    Venezia, Valentina
    Nizzari, Mario
    Carlo, Pia
    Corsaro, Alessandro
    Florio, Tullio
    Russo, Claudio
    NEURODEGENERATIVE DISEASES, 2007, 4 (2-3) : 101 - 111
  • [40] Presenilin dependent γ-secretase processing of β-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch
    Sastre, M
    Steiner, H
    Fuchs, K
    Capell, A
    Multhaup, G
    Condron, MM
    Teplow, DB
    Haass, C
    EMBO REPORTS, 2001, 2 (09) : 835 - 841