Palladium-catalyzed cascade reactions of benzyl halides with N,N-diallyl-p-toluenesulfonamide

被引：2

作者：

Wang, Liansheng ^{[1
,2
]}

Pan, Yi ^{[1
]}

Hu, Hongwen ^{[1
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, Nanjing 210093, Jiangsu, Peoples R China

[2] Hubei Engn Univ, Sch Chem & Mat Sci, Xiaogan 432000, Peoples R China

来源：

HETEROCYCLIC COMMUNICATIONS | 2012年 / 18卷 / 03期

关键词：

alkylation; cyclic cascade reactions; dihydropyrrole; Heck reaction; RING-CLOSING METATHESIS; CYCLIZATION; HETEROCYCLE; VINYLATION; OLEFINS;

D O I：

10.1515/hc-2012-0090

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of N,N-diallyl-p-toluenesulfonamide 1 with benzyl halides 2 in the presence of a palladium catalyst afforded a series of novel dihydropyrroles 3 in moderate yields. A palladium-catalyzed self-cyclization reaction of the diene 1 may take place to give a cyclic dihydropyrrole 4 during the reaction. It is proposed that the cyclic products 4 are formed via a palladium-catalyzed cascade cyclization-coupling process. Reaction of phenyl iodide 5 with 1 in the same condition afforded normal Heck vinylation products 6

引用

页码：147 / 150

页数：4

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