Association factors for atopic dermatitis in nursery school children in Ishigaki islands - Kyushu University Ishigaki Atopic Dermatitis (KIDS) Study

被引:11
作者
Fukiwake, Noriko [1 ]
Furusyo, Norihiro [2 ,3 ]
Takeoka, Hiroaki [2 ,3 ]
Toyoda, Kazuhiro [2 ,3 ]
Kubo, Norihiko [2 ,3 ]
Kido, Makiko [3 ]
Hayashida, Sayaka [3 ]
Uchi, Hiroshi [3 ]
Mori, Yoichi [3 ]
Urabe, Kazunori [3 ]
Kinukawa, Naoko [4 ]
Nose, Yoshiaki [5 ]
Hayashi, Jun [2 ,3 ]
Furue, Masutaka [1 ]
机构
[1] Kyushu Univ Hosp, Dept Dermatol, Higashi Ku, Fukuoka 8128582, Japan
[2] Kyushu Univ Hosp, Dept Med Genet, Higashi Ku, Fukuoka 8128582, Japan
[3] Kyushu Univ, Fac Med Sci, Dept Environm Med & Infect Dis, Higashi Ku, Fukuoka 8128582, Japan
[4] Kyushu Univ Hosp, Dept Med Informat Sci, Higashi Ku, Fukuoka 8128582, Japan
[5] Kyushu Univ, Grad Sch Med Sci, Dept Med Informat, Higashi Ku, Fukuoka 8128582, Japan
关键词
atopic dermatitis; epidemiology; immunoglobulin E; questionnaire; risk factor;
D O I
10.1684/ejd.2008.0479
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Atopic dermatitis (AD) is a multifactorial disease that usually decreases the quality of life of affected patients. The purpose of this study was to evaluate the associated factors for atopic dermatitis, asthma, rhinitis, and food allergy by physical examination of the skin and a questionnaire in nursery school children in Ishigaki Island, Okinawa, Japan. Enrolled in this study were 460 children from 0 to 6 years of age. Physical exaimination of skin symptoms and blood tests were performed. Information on past history and family history of atopic dermatitis. asthma, rhinitis, and food allergy were collected by questionnaire. The prevalence of atopic dermatitis was 12.2% (56/460). The Cumulative prevalence of asthma, and food allergy was 19.9% (91/458), 3.3% (15/457), and 5.5% rhinitis, (25/456), respectively. In multivariate analysis, maternal history of rhinitis, atopic dermatitis siblings, past history of asthma and food allergy, and elevation of total IgE were significantly related to atopic dermatitis. A high total IgE level was a strong risk factor specific for atopic dermatitis in this population.
引用
收藏
页码:571 / 574
页数:4
相关论文
共 24 条
[1]   Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema:: ISAAC [J].
Beasley, R ;
Keil, U ;
von Mutius, E ;
Pearce, N ;
Aït-Khaled, N ;
Anabwani, G ;
Anderson, HR ;
Asher, MI ;
Björkstéin, B ;
Burr, ML ;
Clayton, TO ;
Crane, J ;
Ellwood, P ;
Lai, CKW ;
Mallol, J ;
Martinez, FD ;
Mitchell, EA ;
Montefort, S ;
Robertson, CF ;
Shah, JR ;
Sibbald, B ;
Stewart, AW ;
Strachan, DP ;
Weiland, SK ;
Williams, HC .
LANCET, 1998, 351 (9111) :1225-1232
[2]   Breastfeeding and risk of atopic dermatitis, by parental history of allergy, during the first 18 months of life [J].
Benn, CS ;
Wohlfahrt, J ;
Aaby, P ;
Westergaard, T ;
Benfeldt, E ;
Michaelsen, F ;
Björkstén, B ;
Melbye, M .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2004, 160 (03) :217-223
[3]  
Fukiwake N, 2006, EUR J DERMATOL, V16, P416
[4]   Dosage and adverse effects of topical tacrolimus and steroids in daily management of atopic dermatitis [J].
Furue, M ;
Terao, H ;
Moroi, Y ;
Koga, T ;
Kubota, Y ;
Nakayama, J ;
Furukawa, F ;
Tanaka, Y ;
Katayama, I ;
Kinukawa, N ;
Nose, Y ;
Urabe, K .
JOURNAL OF DERMATOLOGY, 2004, 31 (04) :277-283
[5]   Stabilization of asthma prevalence among adolescents and increase among schoolchildren (ISAAC phases I and III) in Spain [J].
García-Marcos, L ;
Quirós, AB ;
Hernández, GG ;
Guillén-Grima, F ;
Díaz, CG ;
Ureña, IC ;
Pena, AA ;
Monge, RB ;
Suárez-Varela, MM ;
Varela, ALS ;
Cabanillas, PG ;
Garrido, JB .
ALLERGY, 2004, 59 (12) :1301-1307
[6]   Early life risk factors for atopic dermatitis in Ethiopian children [J].
Haileamlak, A ;
Dagoye, D ;
Williams, H ;
Venn, AJ ;
Hubbard, R ;
Britton, J ;
Lewis, SA .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2005, 115 (02) :370-376
[7]   Prevalence of atopic dermatitis and serum IgE values in nursery school children in Ishigaki Island, Okinawa, Japan [J].
Hamada, M ;
Furusyo, N ;
Urabe, K ;
Morita, K ;
Nakahara, T ;
Kinukawa, N ;
Nose, Y ;
Hayashi, J ;
Furue, M .
JOURNAL OF DERMATOLOGY, 2005, 32 (04) :248-255
[8]  
Hikino S, 2001, ACTA PAEDIATR, V90, P850, DOI 10.1080/08035250152509537
[9]   The genetics of atopic dermatitis: recent findings and future options [J].
Hoffjan, S ;
Epplen, JT .
JOURNAL OF MOLECULAR MEDICINE-JMM, 2005, 83 (09) :682-692
[10]   The natural course of atopic dermatitis from birth to age 7 years and the association with asthma [J].
Illi, S ;
von Mutius, E ;
Lau, S ;
Nickel, R ;
Grüber, C ;
Niggemann, B ;
Wahn, U .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2004, 113 (05) :925-931