Catalytic enantioselective aldol additions of α-isothiocyanato imides to aldehydes

被引：88

作者：

Li, Le ^{[1
]}

Klauber, Eric G. ^{[1
]}

Seidel, Daniel ^{[1
]}

机构：

[1] Rutgers State Univ, Dept Chem & Chem Biol, Piscataway, NJ 08854 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 37期

关键词：

D O I：

10.1021/ja804838y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Highly enantioselective organocatalytic aldol additions of aisothiocyanato imides to aldehydes are reported. These reactions provide convenient access to enantiomerically enriched and protected beta-hydroxy-a-amino acids with catalyst loadings as low as 1 mol%.

引用

页码：12248 / +

页数：3

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