Exercise and Nutrition to Target Protein Synthesis Impairments in Aging Skeletal Muscle

被引:1
作者
Dickinson, Jared M. [1 ]
Volpi, Elena [2 ,3 ]
Rasmussen, Blake B. [2 ,4 ,5 ]
机构
[1] Arizona State Univ, Sch Nutr & Hlth Promot, Hlth Lifestyles Res Ctr, Exercise & Wellness Program, Phoenix, AZ 85004 USA
[2] Univ Texas Med Branch, Sealy Ctr Aging, Galveston, TX 77555 USA
[3] Univ Texas Med Branch, Dept Internal Med Geriatr, Galveston, TX 77555 USA
[4] Univ Texas Med Branch, Dept Nutr & Metab, Galveston, TX 77555 USA
[5] Univ Texas Med Branch, Div Rehabil Sci, Galveston, TX 77555 USA
来源
EXERCISE AND SPORT SCIENCES REVIEWS | 2013年 / 41卷 / 04期
基金
美国国家卫生研究院;
关键词
aging; sarcopenia; exercise; protein; insulin; muscle protein synthesis; mTORC1; ESSENTIAL AMINO-ACIDS; RESISTANCE EXERCISE; INSULIN-RESISTANCE; MAMMALIAN TARGET; YOUNG; ANABOLISM; AGE; LEUCINE; MEN; VASODILATION;
D O I
暂无
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
The loss of skeletal muscle size and function with aging and sarcopenia may be related, in part, to an age-related muscle protein synthesis impairment. In this review, we discuss to what extent aging affects skeletal muscle protein synthesis and how nutrition and exercise can be used strategically to overcome age-related protein synthesis impairments and slow the progression of sarcopenia.
引用
收藏
页码:216 / 223
页数:8
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