Efficient racemization of 1-phenylethylamine and its derivatives

被引：3

作者：

Xiong, Xiaoxia ^{[1
]}

Xu, Xinliang ^{[2
]}

Zhou, Yifeng ^{[1
,2
]}

Weng, Chenchen ^{[1
]}

机构：

[1] China Jiliang Univ, Coll Life Sci, Zhejiang Prov Key Lab Biometrol & Inspect & Quara, Hangzhou 310018, Zhejiang, Peoples R China

[2] Zhejiang Apeloa Med Technol Co Ltd, Dongyang 322118, Zhejiang, Peoples R China

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2013年 / 83卷 / 12期

关键词：

DYNAMIC KINETIC RESOLUTION; RADICAL-MEDIATED RACEMIZATION; PRIMARY AMINES; PD; CATALYSIS; ALCOHOLS; LIPASE; METAL;

D O I：

10.1134/S1070363213120359

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report on simple and efficient procedure for the racemization of 1-phenylethylamine and its derivatives. In the presence of trichloroisocyanuric acid, N-chloroimine derivative is formed as the intermediates, with subsequent hydrogenation catalyzed by Pd-C leading to the racemic product.

引用

页码：2402 / 2405

页数：4

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